Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis Y Huang, N Song, Y Ding, S Yuan, X Li, H Cai, H Shi, Y Luo Cancer research 69 (19), 7529-7537, 2009 | 269 | 2009 |
Genetic determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo PK Foggetti G, Li C, Cai H, Hellyer JA, Lin WY, Ayeni D, Hastings K, Choi J ... Cancer Discovery, 2021 | 66 | 2021 |
Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling H Cai, A Liu Proceedings of the National Academy of Sciences 113 (51), 14751-14756, 2016 | 63 | 2016 |
A novel CRYGD mutation (p.Trp43Arg) causing autosomal dominant congenital cataract in a Chinese family B Wang, C Yu, YB Xi, HC Cai, J Wang, S Zhou, S Zhou, Y Wu, YB Yan, ... Human mutation 32 (1), E1939-E1947, 2011 | 60 | 2011 |
Axon-like protrusions promote small cell lung cancer migration and metastasis D Yang, F Qu, H Cai, CH Chuang, JS Lim, N Jahchan, BM Grüner, ... Elife 8, e50616, 2019 | 43 | 2019 |
A novel mutation impairing the tertiary structure and stability of γC‐crystallin (CRYGC) leads to cataract formation in humans and zebrafish lens XQ Li, HC Cai, SY Zhou, JH Yang, YB Xi, XB Gao, WJ Zhao, P Li, ... Human mutation 33 (2), 391-401, 2012 | 43 | 2012 |
A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS–Driven Lung Cancer H Cai, SK Chew, C Li, MK Tsai, L Andrejka, CW Murray, NW Hughes, ... Cancer discovery 11 (7), 1754-1773, 2021 | 34 | 2021 |
A versatile system to record cell-cell interactions R Tang, CW Murray, IL Linde, NJ Kramer, Z Lyu, MK Tsai, LC Chen, H Cai, ... Elife 9, e61080, 2020 | 34 | 2020 |
NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-α Y Ding, Y Huang, N Song, X Gao, S Yuan, X Wang, H Cai, Y Fu, Y Luo The Journal of Immunology 184 (5), 2593-2601, 2010 | 34 | 2010 |
The congenital cataract-linked G61C mutation destabilizes γD-crystallin and promotes non-native aggregation W Zhang, HC Cai, FF Li, YB Xi, X Ma, YB Yan PLoS One 6 (5), e20564, 2011 | 32 | 2011 |
Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord H Cai, A Liu Developmental biology 432 (1), 72-85, 2017 | 24 | 2017 |
Quantitative in vivo analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma C Li, WY Lin, H Rizvi, H Cai, CD McFarland, ZN Rogers, M Yousefi, ... Cancer Research 81 (17), 4570-4580, 2021 | 16 | 2021 |
A multiplexed in vivo approach to identify driver genes in small cell lung cancer MC Lee, H Cai, CW Murray, C Li, YT Shue, L Andrejka, AL He, ... Cell Reports 42 (1), 111990, 2023 | 11 | 2023 |
Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ... Nature Cell Biology 25 (1), 159-169, 2023 | 8 | 2023 |
Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities M Yousefi, G Boross, C Weiss, CW Murray, JD Hebert, H Cai, EL Ashkin, ... Cancer Research 82 (8), 1589-1602, 2022 | 8 | 2022 |
LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer CW Murray, JJ Brady, M Han, H Cai, MK Tsai, SE Pierce, R Cheng, ... Nature communications 13 (1), 1090, 2022 | 6 | 2022 |
Tumor suppressor pathways shape EGFR-driven lung tumor progression and response to treatment G Foggetti, C Li, H Cai, DA Petrov, MM Winslow, K Politi Molecular & Cellular Oncology 9 (1), 1994328, 2022 | | 2022 |
A new system for multiplexed mosaic analysis of gene function in the mouse H Cai, MM Winslow Cell Reports Methods 2 (9), 100295, 2022 | | 2022 |
Dissecting the role of Stag2 in lung adenocarcinoma EL Ashkin, H Cai, YJ Tang, C Li, SK Chew, K Hung, J Belk, S Karmakar, ... Cancer Research 82 (12_Supplement), 821-821, 2022 | | 2022 |
A journey to deconvolute the multifaceted functions and context-dependency of cancer driver genes H Cai, SK Chew, C Li, CW Murray, L Andrejka, JD Hebert, MK Tsai, ... Cancer Research 82 (12_Supplement), 827-827, 2022 | | 2022 |