Acid-mediated tumor proteolysis: contribution of cysteine cathepsins JM Rothberg, KM Bailey, JW Wojtkowiak, Y Ben-Nun, M Bogyo, E Weber, ... Neoplasia 15 (10), 1125-IN9, 2013 | 120 | 2013 |
Macrophage-induced lymphangiogenesis and metastasis following paclitaxel chemotherapy is regulated by VEGFR3 D Alishekevitz, S Gingis-Velitski, O Kaidar-Person, L Gutter-Kapon, ... Cell reports 17 (5), 1344-1356, 2016 | 106 | 2016 |
A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression SJ Salpeter, Y Pozniak, E Merquiol, Y Ben-Nun, T Geiger, G Blum Oncogene 34 (50), 6066-6078, 2015 | 66 | 2015 |
Characterizing cathepsin activity and macrophage subtypes in excised human carotid plaques I Abd-Elrahman, K Meir, H Kosuge, Y Ben-Nun, T Weiss Sadan, ... Stroke 47 (4), 1101-1108, 2016 | 62 | 2016 |
Molecular imaging of cancer using X-ray computed tomography with protease targeted iodinated activity-based probes HK Gaikwad, D Tsvirkun, Y Ben-Nun, E Merquiol, R Popovtzer, G Blum Nano letters 18 (3), 1582-1591, 2018 | 61 | 2018 |
CT imaging of enzymatic activity in cancer using covalent probes reveal a size-dependent pattern D Tsvirkun, Y Ben-Nun, E Merquiol, I Zlotver, K Meir, T Weiss-Sadan, ... Journal of the American Chemical Society 140 (38), 12010-12020, 2018 | 59 | 2018 |
Detecting cathepsin activity in human osteoarthritis via activity-based probes L Ben-Aderet, E Merquiol, D Fahham, A Kumar, E Reich, Y Ben-Nun, ... Arthritis research & therapy 17, 1-14, 2015 | 58 | 2015 |
Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins R Blau, Y Epshtein, E Pisarevsky, G Tiram, SI Dangoor, E Yeini, ... Theranostics 8 (13), 3437, 2018 | 55 | 2018 |
Photodynamic quenched cathepsin activity based probes for cancer detection and macrophage targeted therapy Y Ben-Nun, E Merquiol, A Brandis, B Turk, A Scherz, G Blum Theranostics 5 (8), 847, 2015 | 52 | 2015 |
Homogeneous oligomers of pro-apoptotic BAX reveal structural determinants of mitochondrial membrane permeabilization ZJ Hauseman, EP Harvey, CE Newman, TE Wales, JC Bucci, J Mintseris, ... Molecular cell 79 (1), 68-83. e7, 2020 | 44 | 2020 |
Cathepsin activity-based probes and inhibitor for preclinical atherosclerosis imaging and macrophage depletion I Abd-Elrahman, H Kosuge, T Wises Sadan, Y Ben-Nun, K Meir, ... PLoS One 11 (8), e0160522, 2016 | 39 | 2016 |
Cathepsin nanofiber substrates as potential agents for targeted drug delivery Y Ben-Nun, G Fichman, L Adler-Abramovich, B Turk, E Gazit, G Blum Journal of Controlled Release 257, 60-67, 2017 | 35 | 2017 |
Cathepsins drive anti-inflammatory activity by regulating autophagy and mitochondrial dynamics in macrophage foam cells T Weiss-Sadan, D Maimoun, D Oelschlagel, F Kaschani, D Misiak, ... Cell Physiol Biochem 53 (3), 550-72, 2019 | 23 | 2019 |
A theranostic cathepsin activity-based probe for noninvasive intervention in cardiovascular diseases T Weiss-Sadan, Y Ben-Nun, D Maimoun, E Merquiol, I Abd-Elrahman, ... Theranostics 9 (20), 5731, 2019 | 23 | 2019 |
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation [S] T Weiss-Sadan, G Itzhak, F Kaschani, Z Yu, M Mahameed, A Anaki, ... Molecular & Cellular Proteomics 18 (7), 1330-1344, 2019 | 9 | 2019 |
mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity NK Meena, SP Pattanayak, Y Ben‐Nun, S Benhamron, S Kumar, ... Immunology 155 (4), 505-518, 2018 | 4 | 2018 |
Identification of a structural determinant for selective targeting of HDMX Y Ben-Nun, HS Seo, EP Harvey, ZJ Hauseman, TE Wales, CE Newman, ... Structure 28 (7), 847-857. e5, 2020 | 3 | 2020 |
Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction U Adhikary, JA Paulo, M Godes, S Roychoudhury, MS Prew, Y Ben-Nun, ... Cell Reports 42 (10), 2023 | 2 | 2023 |
Structurally-stabilized and hdmx-selective p53 peptides and uses thereof LD Walensky, BENNUN Yael, HD Herce US Patent App. 17/920,503, 2023 | | 2023 |
Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride BCO Rocha, GP Perecim, C Raminelli SynOpen 3 (04), 142-147, 2019 | | 2019 |