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Gerald S. Shadel
Gerald S. Shadel
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Alıntı yapanlar
Alıntı yapanlar
Yıl
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
AP West, IE Brodsky, C Rahner, DK Woo, H Erdjument-Bromage, ...
Nature 472 (7344), 476-480, 2011
16252011
Mitochondrial DNA stress primes the antiviral innate immune response
AP West, W Khoury-Hanold, M Staron, MC Tal, S Pineda C, Lang, ...
Nature 520 (7548), 533-537, 2015
14572015
Mitochondria in innate immune responses
AP West, GS Shadel, S Ghosh
Nature Reviews Immunology 11 (6), 389-402, 2011
13962011
Mitochondrial DNA maintenance in vertebrates
GS Shadel, DA Clayton
Annual review of biochemistry 66 (1), 409-435, 1997
13241997
Mitochondrial ROS signaling in organismal homeostasis
GS Shadel, TL Horvath
Cell 163 (3), 560-569, 2015
11052015
Mitochondrial DNA in innate immune responses and inflammatory pathology
AP West, GS Shadel
Nature Reviews Immunology 17 (6), 363-375, 2017
7722017
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
A Rongvaux, R Jackson, CCD Harman, T Li, AP West, MR De Zoete, ...
Cell 159 (7), 1563-1577, 2014
7082014
Replicative and chronological aging in Saccharomyces cerevisiae
VD Longo, GS Shadel, M Kaeberlein, B Kennedy
Cell metabolism 16 (1), 18-31, 2012
6702012
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
MC Tal, M Sasai, HK Lee, B Yordy, GS Shadel, A Iwasaki
Proceedings of the National Academy of Sciences 106 (8), 2770-2775, 2009
6302009
Interventions to slow aging in humans: are we ready?
VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ...
Aging cell 14 (4), 497-510, 2015
5982015
SARS-CoV-2 spike protein impairs endothelial function via downregulation of ACE 2
Y Lei, J Zhang, CR Schiavon, M He, L Chen, H Shen, Y Zhang, Q Yin, ...
Circulation research 128 (9), 1323-1326, 2021
5322021
Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression
ND Bonawitz, M Chatenay-Lapointe, Y Pan, GS Shadel
Cell metabolism 5 (4), 265-277, 2007
5172007
Initiation and beyond: multiple functions of the human mitochondrial transcription machinery
ND Bonawitz, DA Clayton, GS Shadel
Molecular cell 24 (6), 813-825, 2006
4352006
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance
HY Lee, CS Choi, AL Birkenfeld, TC Alves, FR Jornayvaz, MJ Jurczak, ...
Cell metabolism 12 (6), 668-674, 2010
3472010
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling
Y Pan, EA Schroeder, A Ocampo, A Barrientos, GS Shadel
Cell metabolism 13 (6), 668-678, 2011
3432011
Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744.
JH Devine, GS Shadel, TO Baldwin
Proceedings of the National Academy of Sciences 86 (15), 5688-5692, 1989
3171989
Revisiting the TCA cycle: signaling to tumor formation
N Raimundo, BE Baysal, GS Shadel
Trends in molecular medicine 17 (11), 641-649, 2011
2772011
A Human Mitochondrial Transcription Factor Is Related to RNA Adenine Methyltransferases and Binds S-Adenosylmethionine
V McCulloch, BL Seidel-Rogol, GS Shadel
Molecular and cellular biology 22 (4), 1116-1125, 2002
2672002
Mitochondrial transcription initiation. Variation and conservation
GS Shadel, DA Clayton
Journal of Biological Chemistry 268 (22), 16083-16086, 1993
2461993
Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator
DJ Dairaghi, GS Shadel, DA Clayton
Journal of molecular biology 249 (1), 11-28, 1995
2441995
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