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Pinar Obakan Yerlikaya
Pinar Obakan Yerlikaya
Istanbul Medeniyet University, Dept. of Molecular Biology and Genetics
Verified email at medeniyet.edu.tr
Title
Cited by
Cited by
Year
Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells
Y Akkoç, Ö Berrak, ED Arısan, P Obakan, A Çoker-Gürkan, ...
Biomedicine & Pharmacotherapy 71, 161-171, 2015
792015
The inhibition of PI3K and NFκB promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells
Ö Berrak, Y Akkoç, ED Arısan, A Çoker-Gürkan, P Obakan-Yerlikaya, ...
Biomedicine & Pharmacotherapy 77, 150-160, 2016
672016
Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-κB signaling and polyamine metabolism in breast cancer cells
A Coker-Gurkan, M Celik, M Ugur, ED Arisan, P Obakan-Yerlikaya, ...
Amino acids 50, 1045-1069, 2018
542018
CDK inhibitors induce mitochondria-mediated apoptosis through the activation of polyamine catabolic pathway in LNCaP, DU145 and PC3 prostate cancer cells
E Damla Arisan, P Obakan, A Coker-Gurkan, A Calcabrini, E Agostinelli, ...
Current pharmaceutical design 20 (2), 180-188, 2014
472014
Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines
P Obakan, ED Arisan, A Calcabrini, E Agostinelli, Ş Bolkent, ...
Amino acids 46, 553-564, 2014
432014
Curcumin prevented human autocrine growth hormone (GH) signaling mediated NF-κB activation and miR-183-96-182 cluster stimulated epithelial mesenchymal transition in T47D …
A Coker-Gurkan, D Bulut, R Genc, ED Arisan, P Obakan-Yerlikaya, ...
Molecular biology reports 46 (1), 355-369, 2019
412019
Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells
A Coker-Gurkan, ED Arisan, P Obakan, E Guvenir, NP Unsal
Experimental Cell Research 328 (1), 87-98, 2014
402014
Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells
D Coskun, P Obakan, ED Arisan, A Çoker-Gürkan, N Palavan-Ünsal
Experimental cell research 338 (1), 10-21, 2015
372015
Calreticulin is a fine tuning molecule in epibrassinolide‐induced apoptosis through activating endoplasmic reticulum stress in colon cancer cells
P Obakan‐Yerlikaya, ED Arisan, A Coker‐Gurkan, K Adacan, U Ozbey, ...
Molecular Carcinogenesis 56 (6), 1603-1619, 2017
322017
Epibrassinolide‐induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate …
P Obakan, ED Arisan, A Coker‐Gurkan, N Palavan‐Unsal
The Prostate 74 (16), 1622-1633, 2014
302014
Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells
ED Arisan, Z Ergül, G Bozdağ, Ö Rencüzoğulları, A Çoker-Gürkan, ...
Molecular biology reports 45 (6), 2175-2184, 2018
292018
Palbociclib, a selective CDK4/6 inhibitor, restricts cell survival and epithelial‐mesenchymal transition in Panc‐1 and MiaPaCa‐2 pancreatic cancer cells
O Rencuzogulları, PO Yerlikaya, AÇ Gürkan, ED Arısan, D Telci
Journal of cellular biochemistry 121 (1), 508-523, 2020
272020
Inhibition of ornithine decarboxylase alters the roscovitine-induced mitochondrial-mediated apoptosis in MCF-7 breast cancer cells
E Damla Arisan, P Obakan, A Coker, N Palavan-Unsal
Molecular Medicine Reports 5 (5), 1323-1329, 2012
272012
SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells
P Obakan, C Barrero, A Coker-Gurkan, ED Arisan, S Merali, ...
PloS One, doi: 10.1371/journal.pone.0135788, 2015
262015
Breast cancer and flavonoids as treatment strategy
P Obakan-Yerlikaya, ED Arisan, A Coker-Gurkan, N Palavan-Unsal
Breast Cancer Biol. Med 5, 305-326, 2017
212017
mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells
O Berrak, ED Arisan, P Obakan-Yerlikaya, A Coker-Gürkan, ...
Apoptosis 21, 1158-1178, 2016
212016
Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells
A Coker-Gürkan, ED Arisan, P Obakan, K Akalın, U Özbey, ...
Oncology Reports 33 (6), 2761-2770, 2015
212015
Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells
P Obakan, ED Arısan, P Özfiliz, A Çoker-Gürkan, N Palavan-Ünsal
Molecular biology reports 41, 145-154, 2014
192014
Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways
A Coker‐Gurkan, B Ayhan‐Sahin, G Keceloglu, P Obakan‐Yerlikaya, ...
Journal of cellular biochemistry 120 (12), 19749-19763, 2019
182019
Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner
AC Gurkan, ED Arisan, PO Yerlikaya, H Ilhan, NP Unsal
Cellular Oncology 41, 297-317, 2018
162018
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