Native chemical ligation and extended methods: mechanisms, catalysis, scope, and limitations V Agouridas, O El Mahdi, V Diemer, M Cargoet, JCM Monbaliu, O Melnyk Chemical reviews 119 (12), 7328-7443, 2019 | 519 | 2019 |
Bis (2-sulfanylethyl) amino native peptide ligation N Ollivier, J Dheur, R Mhidia, A Blanpain, O Melnyk Organic letters 12 (22), 5238-5241, 2010 | 252 | 2010 |
Sequential native peptide ligation strategies for total chemical protein synthesis L Raibaut, N Ollivier, O Melnyk Chemical Society Reviews 41 (21), 7001-7015, 2012 | 245 | 2012 |
A one‐pot three‐segment ligation strategy for protein chemical synthesis N Ollivier, J Vicogne, A Vallin, H Drobecq, R Desmet, O El Mahdi, ... Angewandte Chemie 124 (1), 213-217, 2012 | 148 | 2012 |
Matrix-free laser desorption/ionization mass spectrometry on silicon nanowire arrays prepared by chemical etching of crystalline silicon G Piret, H Drobecq, Y Coffinier, O Melnyk, R Boukherroub Langmuir 26 (2), 1354-1361, 2010 | 137 | 2010 |
Fmoc Solid-Phase Synthesis of Peptide Thioesters Using an Intramolecular N,S-Acyl Shift N Ollivier, JB Behr, O El-Mahdi, A Blanpain, O Melnyk Organic Letters 7 (13), 2647-2650, 2005 | 137 | 2005 |
Peptide− protein microarrays for the simultaneous detection of pathogen infections X Duburcq, C Olivier, F Malingue, R Desmet, A Bouzidi, F Zhou, C Auriault, ... Bioconjugate chemistry 15 (2), 307-316, 2004 | 131 | 2004 |
Peptide arrays for highly sensitive and specific antibody-binding fluorescence assays O Melnyk, X Duburcq, C Olivier, F Urbès, C Auriault, H Gras-Masse Bioconjugate chemistry 13 (4), 713-720, 2002 | 103 | 2002 |
α-Oxo aldehyde or glyoxylyl group chemistry in peptide bioconjugation O El-Mahdi, O Melnyk Bioconjugate chemistry 24 (5), 735-765, 2013 | 96 | 2013 |
High sensitive matrix-free mass spectrometry analysis of peptides using silicon nanowires-based digital microfluidic device F Lapierre, G Piret, H Drobecq, O Melnyk, Y Coffinier, V Thomy, ... Lab on a Chip 11 (9), 1620-1628, 2011 | 88 | 2011 |
Biomolecule and nanoparticle transfer on patterned and heterogeneously wetted superhydrophobic silicon nanowire surfaces G Piret, Y Coffinier, C Roux, O Melnyk, R Boukherroub Langmuir 24 (5), 1670-1672, 2008 | 87 | 2008 |
One‐pot synthesis of antigen‐bearing, lysine‐based cluster mannosides using two orthogonal chemoselective ligation reactions C Grandjean, C Rommens, H Gras‐Masse, O Melnyk Angewandte Chemie 112 (6), 1110-1114, 2000 | 84 | 2000 |
Diamond nanowires for highly sensitive matrix-free mass spectrometry analysis of small molecules Y Coffinier, S Szunerits, H Drobecq, O Melnyk, R Boukherroub Nanoscale 4 (1), 231-238, 2012 | 82 | 2012 |
A statistical view of protein chemical synthesis using NCL and extended methodologies V Agouridas, O El Mahdi, M Cargoët, O Melnyk Bioorganic & Medicinal Chemistry 25 (18), 4938-4945, 2017 | 80 | 2017 |
The deprotection of Lys (Mtt) revisited L Bourel, O Carion, H Gras‐Masse, O Melnyk Journal of Peptide Science: An Official Publication of the European Peptide …, 2000 | 79 | 2000 |
Synthesis of Peptide Alkylthioesters Using the Intramolecular N,S-Acyl Shift Properties of Bis(2-sulfanylethyl)amido Peptides J Dheur, N Ollivier, A Vallin, O Melnyk The Journal of Organic Chemistry 76 (9), 3194-3202, 2011 | 78 | 2011 |
One-pot chemical synthesis of small ubiquitin-like modifier protein–peptide conjugates using bis(2-sulfanylethyl)amido peptide latent thioester surrogates E Boll, H Drobecq, N Ollivier, A Blanpain, L Raibaut, R Desmet, J Vicogne, ... Nature protocols 10 (2), 269-292, 2015 | 77 | 2015 |
Solid phase protein chemical synthesis L Raibaut, O El Mahdi, O Melnyk Protein Ligation and Total Synthesis II, 103-154, 2015 | 69 | 2015 |
Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis (2-sulfanylethyl) amido (SEA) peptide segments L Raibaut, H Adihou, R Desmet, AF Delmas, V Aucagne, O Melnyk Chemical Science 4 (10), 4061-4066, 2013 | 69 | 2013 |
Synthesis of thiazolidine thioester peptides and acceleration of native chemical ligation J Dheur, N Ollivier, O Melnyk Organic Letters 13 (6), 1560-1563, 2011 | 69 | 2011 |