TGFβ: a sleeping giant awoken by integrins JJ Worthington, JE Klementowicz, MA Travis Trends in biochemical sciences 36 (1), 47-54, 2011 | 284 | 2011 |
Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity JJ Worthington, F Reimann, FM Gribble Mucosal immunology 11 (1), 3-20, 2018 | 245 | 2018 |
Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance. RIS Houlden A, Hayes KS, Bancroft AJ, Worthington JJ, Wang P, Grencis RK Plos One 10 (5), e0125945, 2015 | 210 | 2015 |
Intestinal dendritic cells specialize to activate transforming growth factor-β and induce Foxp3+ regulatory T cells via integrin αvβ8 JJ Worthington, BI Czajkowska, AC Melton, MA Travis Gastroenterology 141 (5), 1802-1812, 2011 | 201 | 2011 |
Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation. JJ Worthington, A Kelly, C Smedley, D Bauché, S Campbell, JC Marie, ... Immunity 42 (5), 903-915, 2015 | 196 | 2015 |
Nesfatin-1, a unique regulatory neuropeptide of the brain A Pałasz, M Krzystanek, J Worthington, B Czajkowska, K Kostro, ... Neuropeptides 46 (3), 105-112, 2012 | 145 | 2012 |
Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells JJ Worthington, TM Fenton, BI Czajkowska, JE Klementowicz, MA Travis Immunobiology 217 (12), 1259-1265, 2012 | 135 | 2012 |
Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders? GW Moran, FC Leslie, SE Levison, JJ Worthington, JT McLaughlin Therapeutic advances in gastroenterology 1 (1), 51-60, 2008 | 128 | 2008 |
The intestinal immunoendocrine axis-novel cross talk between enteroendocrine cells and the immune system during infection and inflammatory disease. JJ Worthington Biochemical Society Transactions 43 (4), 727–733, 2015 | 123 | 2015 |
WSX-1: a key role in induction of chronic intestinal nematode infection AJ Bancroft, NE Humphreys, JJ Worthington, H Yoshida, RK Grencis The Journal of Immunology 172 (12), 7635-7641, 2004 | 77 | 2004 |
Molecular Characterization and Expression of Urotensin II and its Receptor in the Flounder (Platichthys flesus): A Hormone System Supporting Body Fluid … W Lu, M Greenwood, L Dow, J Yuill, J Worthington, MJ Brierley, ... Endocrinology 147 (8), 3692-3708, 2006 | 69 | 2006 |
Trichinella spiralis antigens prime mixed Th1/Th2 response but do not induce de novo generation of Foxp3+ T cells in vitro N Ilic, JJ Worthington, A Gruden‐Movsesijan, MA Travis, ... Parasite Immunology 33 (10), 572-582, 2011 | 68 | 2011 |
Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8 TM Fenton, A Kelly, EE Shuttleworth, C Smedley, A Atakilit, F Powrie, ... Mucosal immunology 10 (3), 624-634, 2017 | 67 | 2017 |
The novel neuropeptide phoenixin is highly co-expressed with nesfatin-1 in the rat hypothalamus, an immunohistochemical study RW Artur Pałasza, Ewa Rojczyka, Katarzyna Bogusa, John J. Worthington Neuroscience Letters 592, 17-21, 2015 | 63 | 2015 |
The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa A Pałasz, M Janas-Kozik, A Borrow, O Arias-Carrión, JJ Worthington Neurochemistry international 113, 120-136, 2018 | 56 | 2018 |
Tuft cells: a new flavor in innate epithelial immunity RK Grencis, JJ Worthington Trends in parasitology 32 (8), 583-585, 2016 | 48 | 2016 |
Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion JJ Worthington, LC Samuelson, RK Grencis, JT McLaughlin PLoS Pathogens 9 (1), e1003122, 2013 | 48 | 2013 |
Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity JJ Worthington, JE Klementowicz, S Rahman, BI Czajkowska, C Smedley, ... PLoS pathogens 9 (10), e1003675, 2013 | 45 | 2013 |
Seasonal changes in peptide, receptor and ion channel mRNA expression in the caudal neurosecretory system of the European flounder (Platichthys flesus) W Lu, J Worthington, D Riccardi, RJ Balment, CR McCrohan General and comparative endocrinology 153 (1-3), 262-272, 2007 | 38 | 2007 |
Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2 JG Park, FS Oladunni, MA Rohaim, J Whittingham-Dowd, J Tollitt, ... IScience 24 (9), 2021 | 37 | 2021 |