Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers AR de Molina, A Rodrı́guez-González, R Gutiérrez, L Martınez-Pineiro, ... Biochemical and biophysical research communications 296 (3), 580-583, 2002 | 420 | 2002 |
Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives M González-Vallinas, M González-Castejón, A Rodríguez-Casado, ... Nutrition reviews 71 (9), 585-599, 2013 | 311 | 2013 |
Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy A Ramírez de Molina, R Gutiérrez, MA Ramos, JM Silva, J Silva, F Bonilla, ... Oncogene 21 (27), 4317-4322, 2002 | 292 | 2002 |
Dietary strategies implicated in the prevention and treatment of metabolic syndrome R De la Iglesia, V Loria-Kohen, MA Zulet, JA Martinez, G Reglero, ... International Journal of Molecular Sciences 17 (11), 1877, 2016 | 199 | 2016 |
Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study AR de Molina, J Sarmentero-Estrada, C Belda-Iniesta, M Tarón, ... The lancet oncology 8 (10), 889-897, 2007 | 179 | 2007 |
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models NMS Al-Saffar, H Troy, AR de Molina, LE Jackson, B Madhu, JR Griffiths, ... Cancer research 66 (1), 427-434, 2006 | 171 | 2006 |
Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression AR de Molina, M Bánez-Coronel, R Gutiérrez, A Rodríguez-González, ... Cancer research 64 (18), 6732-6739, 2004 | 168 | 2004 |
Regulation of choline kinase activity by Ras proteins involves Ral–GDS and PI3K A Ramírez de Molina, V Penalva, L Lucas, JC Lacal Oncogene 21 (6), 937-946, 2002 | 150 | 2002 |
The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging A Cortés-Martín, R García-Villalba, A González-Sarrías, M Romo-Vaquero, ... Food & function 9 (8), 4100-4106, 2018 | 149 | 2018 |
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy R Sánchez-Martínez, S Cruz-Gil, MG de Cedrón, M Álvarez-Fernández, ... Oncotarget 6 (36), 38719, 2015 | 146 | 2015 |
18F-Choline Images Murine Atherosclerotic Plaques Ex Vivo CM Matter, MT Wyss, P Meier, N Späth, T von Lukowicz, C Lohmann, ... Arteriosclerosis, thrombosis, and vascular biology 26 (3), 584-589, 2006 | 139 | 2006 |
Alterations of lipid metabolism in cancer: implications in prognosis and treatment LP Fernández, M Gomez de Cedron, A Ramirez de Molina Frontiers in oncology 10, 577420, 2020 | 135 | 2020 |
Lipid metabolism and lung cancer MM Salvador, MG de Cedrón, JM Rubio, SF Martínez, RS Martínez, ... Critical reviews in oncology/hematology 112, 31-40, 2017 | 131 | 2017 |
Antitumor effect of 5-fluorouracil is enhanced by rosemary extract in both drug sensitive and resistant colon cancer cells M Gonzalez-Vallinas, S Molina, G Vicente, A de la Cueva, T Vargas, ... Pharmacological research 72, 61-68, 2013 | 131 | 2013 |
Differential role of human choline kinase α and β enzymes in lipid metabolism: implications in cancer onset and treatment D Gallego-Ortega, A Ramirez de Molina, MA Ramos, F Valdes-Mora, ... PloS one 4 (11), e7819, 2009 | 118 | 2009 |
Rosemary (Rosmarinus officinalis L.) Extract as a Potential Complementary Agent in Anticancer Therapy M González-Vallinas, G Reglero, A Ramírez de Molina Nutrition and cancer 67 (8), 1223-1231, 2015 | 116 | 2015 |
Deciphering the human gut microbiome of urolithin metabotypes: association with enterotypes and potential cardiometabolic health implications M Romo‐Vaquero, A Cortés‐Martín, V Loria‐Kohen, ... Molecular nutrition & food research 63 (4), 1800958, 2019 | 115 | 2019 |
Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of action A Rodríguez-González, A Ramirez de Molina, F Fernandez, JC Lacal Oncogene 23 (50), 8247-8259, 2004 | 109 | 2004 |
Expression of microRNA-15b and the glycosyltransferase GCNT3 correlates with antitumor efficacy of Rosemary diterpenes in colon and pancreatic cancer M Gonzalez-Vallinas, S Molina, G Vicente, V Zarza, R Martin-Hernandez, ... PloS one 9 (6), e98556, 2014 | 107 | 2014 |
Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells A Rodríguez-González, AR De Molina, F Fernandez, MA Ramos, ... Oncogene 22 (55), 8803-8812, 2003 | 107 | 2003 |