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siddharth sukumaran
siddharth sukumaran
Janssen R&D, SUNY Buffalo
Verified email at buffalo.edu
Title
Cited by
Cited by
Year
Membrane-proximal epitope facilitates efficient T cell synapse formation by anti-FcRH5/CD3 and is a requirement for myeloma cell killing
J Li, NJ Stagg, J Johnston, MJ Harris, SA Menzies, D DiCara, V Clark, ...
Cancer cell 31 (3), 383-395, 2017
2462017
Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action
S Sukumaran, RR Almon, DC DuBois, WJ Jusko
Advanced drug delivery reviews 62 (9-10), 904-917, 2010
1752010
An anti-CD3/anti–CLL-1 bispecific antibody for the treatment of acute myeloid leukemia
SR Leong, S Sukumaran, M Hristopoulos, K Totpal, S Stainton, E Lu, ...
Blood, The Journal of the American Society of Hematology 129 (5), 609-618, 2017
1732017
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma
HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ...
Cell 179 (2), 417-431. e19, 2019
882019
Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action
S Sukumaran, WJ Jusko, DC DuBois, RR Almon
Journal of applied physiology 110 (6), 1732-1747, 2011
812011
Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology
S Sukumaran, B Xue, WJ Jusko, DC DuBois, RR Almon
Physiological genomics 42 (2), 141-152, 2010
662010
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
T Sun, Z Huang, WC Liang, J Yin, WY Lin, J Wu, JM Vernes, J Lutman, ...
Science translational medicine 13 (605), eabe0407, 2021
642021
Circadian rhythms: influence on physiology, pharmacology, and therapeutic interventions
VS Ayyar, S Sukumaran
Journal of pharmacokinetics and pharmacodynamics 48, 321-338, 2021
642021
Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats
B Xue, S Sukumaran, J Nie, WJ Jusko, DC DuBois, RR Almon
PLoS one 6 (2), e17386, 2011
642011
Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases
EG Stefanich, J Rae, S Sukumaran, J Lutman, A Lekkerkerker, W Ouyang, ...
Biochemical Pharmacology 152, 224-235, 2018
522018
Mechanism-based pharmacokinetic/pharmacodynamic model for THIOMAB™ drug conjugates
S Sukumaran, K Gadkar, C Zhang, S Bhakta, L Liu, K Xu, H Raab, SF Yu, ...
Pharmaceutical research 32, 1884-1893, 2015
512015
An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans
S Chung, V Nguyen, YL Lin, J Lafrance-Vanasse, SJ Scales, K Lin, ...
MAbs 11 (5), 942-955, 2019
462019
Evidence for a glucocorticoid receptor beta splice variant in the rat and its physiological regulation in liver
DC DuBois, S Sukumaran, WJ Jusko, RR Almon
Steroids 78 (2), 312-320, 2013
452013
Glucocorticoid effects on adiponectin expression
S Sukumaran, DC DuBois, WJ Jusko, RR Almon
Vitamins & Hormones 90, 163-186, 2012
442012
Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by …
E Nouri-Nigjeh, S Sukumaran, C Tu, J Li, X Shen, X Duan, DC DuBois, ...
Analytical chemistry 86 (16), 8149-8157, 2014
412014
Differential muscle gene expression as a function of disease progression in Goto-Kakizaki diabetic rats
J Nie, B Xue, S Sukumaran, WJ Jusko, DC DuBois, RR Almon
Molecular and cellular endocrinology 338 (1-2), 10-17, 2011
402011
Mechanistic modeling of the effects of glucocorticoids and circadian rhythms on adipokine expression
S Sukumaran, WJ Jusko, DC DuBois, RR Almon
Journal of Pharmacology and Experimental Therapeutics 337 (3), 734-746, 2011
342011
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members
Y Yang, SH Yeh, S Madireddi, WL Matochko, C Gu, P Pacheco Sanchez, ...
MAbs 11 (6), 996-1011, 2019
322019
gPKPDSim: a SimBiology®-based GUI application for PKPD modeling in drug development
I Hosseini, A Gajjala, D Bumbaca Yadav, S Sukumaran, S Ramanujan, ...
Journal of pharmacokinetics and pharmacodynamics 45, 259-275, 2018
322018
Circadian signatures in rat liver: from gene expression to pathways
MA Ovacik, S Sukumaran, RR Almon, DC DuBois, WJ Jusko, ...
BMC bioinformatics 11, 1-15, 2010
322010
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Articles 1–20