| α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5′-Nucleotidase (CD73) Inhibitors S Bhattarai, M Freundlieb, J Pippel, A Meyer, A Abdelrahman, A Fiene, ... Journal of medicinal chemistry 58 (15), 6248-6263, 2015 | 144 | 2015 |
| 2-Substituted α, β-methylene-ADP derivatives: Potent competitive ecto-5′-nucleotidase (CD73) inhibitors with variable binding modes S Bhattarai, J Pippel, E Scaletti, R Idris, M Freundlieb, G Rolshoven, ... Journal of medicinal chemistry 63 (6), 2941-2957, 2020 | 44 | 2020 |
| X‐Ray Co‐Crystal Structure Guides the Way to Subnanomolar Competitive Ecto‐5′‐Nucleotidase (CD73) Inhibitors for Cancer Immunotherapy S Bhattarai, J Pippel, A Meyer, M Freundlieb, C Schmies, A Abdelrahman, ... Advanced Therapeutics, 1900075, 2019 | 39 | 2019 |
| Substrate-dependence of competitive nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) inhibitors SY Lee, S Sarkar, S Bhattarai, V Namasivayam, S De Jonghe, H Stephan, ... Frontiers in Pharmacology 8, 238018, 2017 | 36 | 2017 |
| Mechanisms of γ-secretase activation and substrate processing A Bhattarai, S Devkota, S Bhattarai, MS Wolfe, Y Miao ACS central science 6 (6), 969-983, 2020 | 35 | 2020 |
| Mechanism of tripeptide trimming of amyloid β-peptide 49 by γ-secretase A Bhattarai, S Devkota, HN Do, J Wang, S Bhattarai, MS Wolfe, Y Miao Journal of the American Chemical Society 144 (14), 6215-6226, 2022 | 26 | 2022 |
| Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease L Liu, BM Lauro, A He, H Lee, S Bhattarai, MS Wolfe, DA Bennett, ... Alzheimer's & Dementia 19 (1), 79-96, 2023 | 24 | 2023 |
| Reaction on Water: A Greener Approach for the Thia Michael Addition on N-Aryl Maleimides V Kumar, R Mitra, S Bhattarai, VA Nair Synthetic Communications® 41 (3), 392-404, 2011 | 13 | 2011 |
| Design of substrate transmembrane mimetics as structural probes for γ-secretase S Bhattarai, S Devkota, KM Meneely, M Xing, JT Douglas, MS Wolfe Journal of the American Chemical Society 142 (7), 3351-3355, 2020 | 11 | 2020 |
| A facile synthesis and chemoselective reactions of dihydrothiouracils V Kumar, GL Khatik, A Pal, MR Praneeth, S Bhattarai, VA Nair Synlett 23 (16), 2357-2362, 2012 | 10 | 2012 |
| Designed helical peptides as functional probes for γ-secretase AT Philip, S Devkota, S Malvankar, S Bhattarai, KM Meneely, TD Williams, ... Biochemistry 58 (44), 4398-4407, 2019 | 6 | 2019 |
| Design of Transmembrane Mimetic Structural Probes to Trap Different Stages of γ-Secretase–Substrate Interaction S Bhattarai, S Devkota, MS Wolfe Journal of medicinal chemistry 64 (20), 15367-15378, 2021 | 5 | 2021 |
| (Aza)indole-, Benzothiophene-, and benzofuran-3-sulfonamides WO Patent WO/2018/122,232, 2018 | 5* | 2018 |
| Synthesis and Structure-activity Relationships of Alpha, beta-methylene-ADP Derivatives: Potent and Selective Ecto-5′-nucleotidase Inhibitors S Bhattarai Universitäts-und Landesbibliothek Bonn, 2015 | 5 | 2015 |
| Big data in drug discovery S Bhattarai, R Kumar, S Nag, V Namasivayam Machine Learning and Systems Biology in Genomics and Health, 17-48, 2022 | 4 | 2022 |
| Discovery of aryl aminothiazole γ-secretase modulators with novel effects on amyloid β-peptide production S Bhattarai, L Liu, MS Wolfe Bioorganic & medicinal chemistry letters 54, 128446, 2021 | 3 | 2021 |
| Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes S Devkota, R Zhou, V Nagarajan, M Maesako, H Do, A Noorani, ... bioRxiv, 2023.09. 08.556905, 2023 | 2 | 2023 |
| Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes S Devkota, R Zhou, V Nagarajan, M Maesako, H Do, A Noorani, ... Cell Reports 43 (2), 2024 | 1 | 2024 |
| Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides CE Mueller, C Pegurier, MLR Deligny, A El-Tayeb, J Hockemeyer, ... US Patent App. 17/506,331, 2022 | 1 | 2022 |
| Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides CE Mueller, C Pegurier, MLR Deligny, A El-Tayeb, J Hockemeyer, ... US Patent 11,820,746, 2023 | | 2023 |
