PyMod 2.0: improvements in protein sequence-structure analysis and homology modeling within PyMOL G Janson, C Zhang, MG Prado, A Paiardini Bioinformatics 33 (3), 444-446, 2017 | 215 | 2017 |
Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface A Siglioccolo, A Paiardini, M Piscitelli, S Pascarella BMC structural biology 11, 1-12, 2011 | 184 | 2011 |
PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL E Bramucci, A Paiardini, F Bossa, S Pascarella BMC bioinformatics 13, 1-6, 2012 | 172 | 2012 |
Glucose metabolism in the progression of prostate cancer F Cutruzzola, G Giardina, M Marani, A Macone, A Paiardini, S Rinaldo, ... Frontiers in physiology 8, 97, 2017 | 142 | 2017 |
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases G Giardina, R Montioli, S Gianni, B Cellini, A Paiardini, CB Voltattorni, ... Proceedings of the National Academy of sciences 108 (51), 20514-20519, 2011 | 119 | 2011 |
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation A Paone, M Marani, A Fiascarelli, S Rinaldo, G Giardina, R Contestabile, ... Cell death & disease 5 (11), e1525-e1525, 2014 | 118 | 2014 |
l‐Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase: A subgroup of strictly related enzymes specialized for different functions R Contestabile, A Paiardini, S Pascarella, ML di Salvo, S D'Aguanno, ... European Journal of Biochemistry 268 (24), 6508-6525, 2001 | 113 | 2001 |
Human wild-type alanine: glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications B Cellini, M Bertoldi, R Montioli, A Paiardini, C Borri Voltattorni Biochemical Journal 408 (1), 39-50, 2007 | 111 | 2007 |
How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state G Giardina, P Brunotti, A Fiascarelli, A Cicalini, MGS Costa, AM Buckle, ... The FEBS journal 282 (7), 1225-1241, 2015 | 92 | 2015 |
PyMod 3: a complete suite for structural bioinformatics in PyMOL G Janson, A Paiardini Bioinformatics 37 (10), 1471-1472, 2021 | 89 | 2021 |
The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability D Antoniani, E Rossi, S Rinaldo, P Bocci, M Lolicato, A Paiardini, ... Applied microbiology and biotechnology 97, 7325-7336, 2013 | 81 | 2013 |
Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis G Brusotti, R Montanari, D Capelli, G Cattaneo, A Laghezza, P Tortorella, ... Scientific reports 7 (1), 5777, 2017 | 77 | 2017 |
Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors F Daidone, R Montioli, A Paiardini, B Cellini, A Macchiarulo, G Giardina, ... PLoS One 7 (2), e31610, 2012 | 77 | 2012 |
C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG V Stelitano, G Giardina, A Paiardini, N Castiglione, F Cutruzzolà, ... PLoS One 8 (9), e74920, 2013 | 75 | 2013 |
Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection ML di Salvo, R Contestabile, A Paiardini, B Maras Medical hypotheses 80 (5), 633-636, 2013 | 73 | 2013 |
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I B Cellini, R Montioli, A Paiardini, A Lorenzetto, F Maset, T Bellini, E Oppici, ... Proceedings of the National Academy of Sciences 107 (7), 2896-2901, 2010 | 73 | 2010 |
Synthesis and Structure–Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum K Kannan Sivaraman, A Paiardini, M Sienczyk, C Ruggeri, CA Oellig, ... Journal of Medicinal Chemistry 56 (12), 5213-5217, 2013 | 72 | 2013 |
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed F Daidone, R Florio, S Rinaldo, R Contestabile, ML di Salvo, F Cutruzzolà, ... European journal of medicinal chemistry 46 (5), 1616-1621, 2011 | 67 | 2011 |
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed F Daidone, R Florio, S Rinaldo, R Contestabile, ML di Salvo, F Cutruzzolà, ... European journal of medicinal chemistry 46 (5), 1616-1621, 2011 | 67 | 2011 |
N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia Z Ianniello, A Paiardini, A Fatica Frontiers in oncology 9, 251, 2019 | 66 | 2019 |