| Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 791 | 2018 |
| Enhancer reprogramming promotes pancreatic cancer metastasis JS Roe, CI Hwang, TDD Somerville, JP Milazzo, EJ Lee, B Da Silva, ... Cell 170 (5), 875-888. e20, 2017 | 386 | 2017 |
| POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer YH Huang, O Klingbeil, XY He, XS Wu, G Arun, B Lu, TDD Somerville, ... Genes & development 32 (13-14), 915-928, 2018 | 313 | 2018 |
| TP63-mediated enhancer reprogramming drives the squamous subtype of pancreatic ductal adenocarcinoma TDD Somerville, Y Xu, K Miyabayashi, H Tiriac, CR Cleary, D Maia-Silva, ... Cell reports 25 (7), 1741-1755. e7, 2018 | 181 | 2018 |
| LKB1, salt-inducible kinases, and MEF2C are linked dependencies in acute myeloid leukemia Y Tarumoto, B Lu, TDD Somerville, YH Huang, JP Milazzo, XS Wu, ... Molecular cell 69 (6), 1017-1027. e6, 2018 | 131 | 2018 |
| Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes K Miyabayashi, LA Baker, A Deschênes, B Traub, G Caligiuri, D Plenker, ... Cancer discovery 10 (10), 1566-1589, 2020 | 101 | 2020 |
| Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 98 | |
| A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival JG Jude, GJ Spencer, X Huang, TDD Somerville, DR Jones, N Divecha, ... Oncogene 34 (10), 1253-1262, 2015 | 82 | 2015 |
| SOAT1 promotes mevalonate pathway dependency in pancreatic cancer TE Oni, G Biffi, LA Baker, Y Hao, C Tonelli, TDD Somerville, A Deschênes, ... Journal of Experimental Medicine 217 (9), e20192389, 2020 | 77 | 2020 |
| A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia Y Xu, JP Milazzo, TDD Somerville, Y Tarumoto, YH Huang, EL Ostrander, ... Cancer cell 33 (1), 13-28. e8, 2018 | 75 | 2018 |
| Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation TDD Somerville, G Biffi, J Daßler-Plenker, SK Hur, XY He, KE Vance, ... Elife 9, e53381, 2020 | 71 | 2020 |
| Frequent derepression of the mesenchymal transcription factor gene FOXC1 in acute myeloid leukemia TDD Somerville, DH Wiseman, GJ Spencer, X Huang, JT Lynch, ... Cancer cell 28 (3), 329-342, 2015 | 67 | 2015 |
| A transcription factor addiction in leukemia imposed by the MLL promoter sequence B Lu, O Klingbeil, Y Tarumoto, TDD Somerville, YH Huang, Y Wei, ... Cancer Cell 34 (6), 970-981. e8, 2018 | 55 | 2018 |
| ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer TDD Somerville, Y Xu, XS Wu, D Maia-Silva, SK Hur, LMN de Almeida, ... Proceedings of the National Academy of Sciences 117 (21), 11471-11482, 2020 | 43 | 2020 |
| Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells X Huang, GJ Spencer, JT Lynch, F Ciceri, TDD Somerville, ... Leukemia 28 (5), 1081-1091, 2014 | 41 | 2014 |
| BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network X Sun, O Klingbeil, B Lu, C Wu, C Ballon, M Ouyang, XS Wu, Y Jin, ... Nature 613 (7942), 195-202, 2023 | 23 | 2023 |
| Derepression of the Iroquois homeodomain transcription factor gene IRX3 confers differentiation block in acute leukemia TDD Somerville, F Simeoni, JA Chadwick, EL Williams, GJ Spencer, ... Cell Reports 22 (3), 638-652, 2018 | 21 | 2018 |
| Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8 (9): 1112–1129. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 19 | |
| Frequent reconstitution of IDH2R140Q mutant clonal multilineage hematopoiesis following chemotherapy for acute myeloid leukemia DH Wiseman, EL Williams, DP Wilks, H Sun Leong, TDD Somerville, ... Leukemia 30 (9), 1946-1950, 2016 | 17 | 2016 |
| Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov.(2018) 8: 1112–29. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschenes, TDD Somerville, ... CD-18-0349, 0 | 15 | |
