| Locus control region function and heterochromatin-induced position effect variegation R Festenstein, M Tolaini, P Corbella, C Mamalaki, J Parrington, M Fox, ... Science 271 (5252), 1123-1125, 1996 | 439 | 1996 |
| Unravelling heterochromatin: competition between positive and negative factors regulates accessibility N Dillon, R Festenstein TRENDS in Genetics 18 (5), 252-258, 2002 | 356 | 2002 |
| Modulation of heterochromatin protein 1 dynamics in primary mammalian cells R Festenstein, SN Pagakis, K Hiragami, D Lyon, A Verreault, B Sekkali, ... Science 299 (5607), 719-721, 2003 | 337 | 2003 |
| DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing A Saveliev, C Everett, T Sharpe, Z Webster, R Festenstein Nature 422 (6934), 909-913, 2003 | 334 | 2003 |
| H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation B Guillemette, P Drogaris, HHS Lin, H Armstrong, K Hiragami-Hamada, ... PLoS genetics 7 (3), e1001354, 2011 | 230 | 2011 |
| Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals D Kioussis, R Festenstein Current opinion in genetics & development 7 (5), 614-619, 1997 | 187 | 1997 |
| Heterochromatin protein 1: a pervasive controlling influence K Hiragami, R Festenstein Cellular and molecular life sciences CMLS 62, 2711-2726, 2005 | 167 | 2005 |
| Heterochromatin protein 1 modifies mammalian PEV in a dose-and chromosomal-context-dependent manner R Festenstein, S Sharghi-Namini, M Fox, K Roderick, M Tolaini, T Norton, ... Nature genetics 23 (4), 457-461, 1999 | 165 | 1999 |
| Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study V Libri, C Yandim, S Athanasopoulos, N Loyse, T Natisvili, PP Law, ... The Lancet 384 (9942), 504-513, 2014 | 156 | 2014 |
| Epigenetic regulation of autosomal gene expression by sex chromosomes PJ Wijchers, RJ Festenstein Trends in genetics 27 (4), 132-140, 2011 | 154 | 2011 |
| Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation I Taniuchi, MJ Sunshine, R Festenstein, DR Littman Molecular cell 10 (5), 1083-1096, 2002 | 135 | 2002 |
| Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromosome complement as well PJ Wijchers, C Yandim, E Panousopoulou, M Ahmad, N Harker, ... Developmental cell 19 (3), 477-484, 2010 | 133 | 2010 |
| Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication V Azuara, KE Brown, RRE Williams, N Webb, N Dillon, R Festenstein, ... Nature cell biology 5 (7), 668-674, 2003 | 119 | 2003 |
| Continuous histone replacement by Hira is essential for normal transcriptional regulation and de novo DNA methylation during mouse oogenesis B Nashun, PWS Hill, SA Smallwood, G Dharmalingam, R Amouroux, ... Molecular cell 60 (4), 611-625, 2015 | 116 | 2015 |
| Locus control regions and epigenetic chromatin modifiers R Festenstein, D Kioussis Current opinion in genetics & development 10 (2), 199-203, 2000 | 103 | 2000 |
| Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3 PK Chan, R Torres, C Yandim, PP Law, S Khadayate, M Mauri, C Grosan, ... Human molecular genetics 22 (13), 2662-2675, 2013 | 95 | 2013 |
| Whole genome sequencing for the diagnosis of neurological repeat expansion disorders in the UK: a retrospective diagnostic accuracy and prospective clinical validation study K Ibañez, J Polke, RT Hagelstrom, E Dolzhenko, D Pasko, ERA Thomas, ... The Lancet Neurology 21 (3), 234-245, 2022 | 89 | 2022 |
| Human HMG box transcription factor HBP1: a role in hCD2 LCR function T Zhuma, R Tyrrell, B Sekkali, G Skavdis, A Saveliev, M Tolaini, ... The EMBO Journal, 1999 | 82 | 1999 |
| Gene regulation and epigenetics in Friedreich's ataxia C Yandim, T Natisvili, R Festenstein Journal of neurochemistry 126, 21-42, 2013 | 81 | 2013 |
| A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice. A Hostert, M Tolaini, R Festenstein, L McNeill, B Malissen, O Williams, ... Journal of immunology (Baltimore, Md.: 1950) 158 (9), 4270-4281, 1997 | 79 | 1997 |
