Takip et
Matthew Auton
Matthew Auton
mayo.edu üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Predicting the energetics of osmolyte-induced protein folding/unfolding
M Auton, DW Bolen
Proceedings of the National Academy of Sciences 102 (42), 15065-15068, 2005
5052005
Anatomy of energetic changes accompanying urea-induced protein denaturation
M Auton, LMF Holthauzen, DW Bolen
Proceedings of the National Academy of Sciences 104 (39), 15317-15322, 2007
3232007
Osmolyte effects on protein stability and solubility: A balancing act between backbone and side-chains
M Auton, J Rösgen, M Sinev, LMF Holthauzen, DW Bolen
Biophysical chemistry 159 (1), 90-99, 2011
2532011
Additive transfer free energies of the peptide backbone unit that are independent of the model compound and the choice of concentration scale
M Auton, DW Bolen
Biochemistry 43 (5), 1329-1342, 2004
2522004
Structural thermodynamics of protein preferential solvation: osmolyte solvation of proteins, aminoacids, and peptides
M Auton, DW Bolen, J Rösgen
Proteins: Structure, Function, and Bioinformatics 73 (4), 802-813, 2008
1982008
Application of the transfer model to understand how naturally occurring osmolytes affect protein stability
M Auton, DW Bolen
Methods in enzymology 428, 397-418, 2007
1162007
Conformational stability and domain unfolding of the Von Willebrand factor A domains
M Auton, MA Cruz, J Moake
Journal of molecular biology 366 (3), 986-1000, 2007
1122007
Metrics that differentiate the origins of osmolyte effects on protein stability: a test of the surface tension proposal
M Auton, ACM Ferreon, DW Bolen
Journal of molecular biology 361 (5), 983-992, 2006
1062006
Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations
LM Blancas-Mejía, A Tischer, JR Thompson, J Tai, L Wang, M Auton, ...
Journal of molecular biology 426 (2), 347-361, 2014
582014
N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress
M Auton, KE Sowa, M Behymer, MA Cruz
Journal of Biological Chemistry 287 (18), 14579-14585, 2012
582012
The mechanism of VWF-mediated platelet GPIbα binding
M Auton, C Zhu, MA Cruz
Biophysical journal 99 (4), 1192-1201, 2010
532010
Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding
LM Blancas-Mejía, TJ Horn, M Marin-Argany, M Auton, A Tischer, ...
Biophysical chemistry 207, 13-20, 2015
512015
Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibα and platelet activation under …
M Auton, KE Sowa, SM Smith, E Sedlák, KV Vijayan, MA Cruz
Journal of biological chemistry 285 (30), 22831-22839, 2010
492010
Changes in thermodynamic stability of von Willebrand factor differentially affect the force-dependent binding to platelet GPIbα
M Auton, E Sedlák, J Marek, T Wu, C Zhu, MA Cruz
Biophysical journal 97 (2), 618-627, 2009
482009
The linker between the d3 and a1 domains of vwf suppresses a1‐GPIbα catch bonds by site‐specific binding to the a1 domain
A Tischer, MA Cruz, M Auton
Protein Science 22 (8), 1049-1059, 2013
392013
Misfolding of vWF to pathologically disordered conformations impacts the severity of von Willebrand disease
A Tischer, P Madde, L Moon-Tasson, M Auton
Biophysical journal 107 (5), 1185-1195, 2014
382014
Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins
RB Perez, A Tischer, M Auton, ST Whitten
Proteins: Structure, Function, and Bioinformatics 82 (12), 3373-3384, 2014
352014
The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction
R Schneppenheim, N Hellermann, MA Brehm, U Klemm, T Obser, V Huck, ...
Blood, The Journal of the American Society of Hematology 133 (4), 356-365, 2019
342019
Mutational constraints on local unfolding inhibit the rheological adaptation of von Willebrand factor
A Tischer, JC Campbell, VR Machha, L Moon-Tasson, LM Benson, ...
Journal of Biological Chemistry 291 (8), 3848-3859, 2016
302016
Protein stability in the presence of cosolutes
LMF Holthauzen, M Auton, M Sinev, J Rösgen
Methods in Enzymology 492, 61-125, 2011
302011
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