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karen duff
karen duff
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13058*2021
Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
D Morgan, DM Diamond, PE Gottschall, KE Ugen, C Dickey, J Hardy, ...
Nature 408 (6815), 982-985, 2000
21302000
Increased amyloid-β42 (43) in brains of mice expressing mutant presenilin 1
K Duff, C Eckman, C Zehr, X Yu, CM Prada, J Perez-Tur, M Hutton, L Buee, ...
Nature 383 (6602), 710-713, 1996
20391996
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
L Holcomb, MN Gordon, E McGowan, X Yu, S Benkovic, P Jantzen, ...
Nature medicine 4 (1), 97-100, 1998
17141998
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
J Lewis, E McGowan, J Rockwood, H Melrose, P Nacharaju, ...
Nature genetics 25 (4), 402-405, 2000
16072000
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
LM Refolo, MA Pappolla, B Malester, J LaFrancois, T Bryant-Thomas, ...
Neurobiology of disease 7 (4), 321-331, 2000
13182000
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ...
The Journal of cell biology 171 (1), 87-98, 2005
11532005
Trans-synaptic spread of tau pathology in vivo
L Liu, V Drouet, JW Wu, MP Witter, SA Small, C Clelland, K Duff
PloS one 7 (2), e31302, 2012
11252012
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
W Noble, E Planel, C Zehr, V Olm, J Meyerson, F Suleman, K Gaynor, ...
Proceedings of the national academy of sciences 102 (19), 6990-6995, 2005
9122005
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
CA Saura, SY Choi, V Beglopoulos, S Malkani, D Zhang, BSS Rao, ...
Neuron 42 (1), 23-36, 2004
8862004
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
C Andorfer, Y Kress, M Espinoza, R De Silva, KL Tucker, YA Barde, K Duff, ...
Journal of neurochemistry 86 (3), 582-590, 2003
8552003
Linking Aβ and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
SA Small, K Duff
Neuron 60 (4), 534-542, 2008
7292008
A cholesterol-lowering drug reduces β-amyloid pathology in a transgenic mouse model of Alzheimer's disease
LM Refolo, MA Pappolla, J LaFrancois, B Malester, SD Schmidt, ...
Neurobiology of disease 8 (5), 890-899, 2001
7012001
Neuronal activity enhances tau propagation and tau pathology in vivo
JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ...
Nature neuroscience 19 (8), 1085-1092, 2016
6722016
Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
J Tsai, J Grutzendler, K Duff, WB Gan
Nature neuroscience 7 (11), 1181-1183, 2004
6672004
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
C Andorfer, CM Acker, Y Kress, PR Hof, K Duff, P Davies
Journal of Neuroscience 25 (22), 5446-5454, 2005
6102005
Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease
UA Khan, L Liu, FA Provenzano, DE Berman, CP Profaci, R Sloan, ...
Nature neuroscience 17 (2), 304-311, 2014
6092014
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease
RB Chan, TG Oliveira, EP Cortes, LS Honig, KE Duff, SA Small, MR Wenk, ...
Journal of Biological Chemistry 287 (4), 2678-2688, 2012
5802012
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
W Noble, V Olm, K Takata, E Casey, O Mary, J Meyerson, K Gaynor, ...
Neuron 38 (4), 555-565, 2003
5772003
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
JW Wu, M Herman, L Liu, S Simoes, CM Acker, H Figueroa, JI Steinberg, ...
Journal of Biological Chemistry 288 (3), 1856-1870, 2013
5652013
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