Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein AE Barry, I Klyubin, JM Mc Donald, AJ Mably, MA Farrell, M Scott, ... Journal of Neuroscience 31 (20), 7259-7263, 2011 | 283 | 2011 |
Gamma oscillations in cognitive disorders AJ Mably, LL Colgin Current opinion in neurobiology 52, 182-187, 2018 | 211 | 2018 |
mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo NW Hu, AJ Nicoll, D Zhang, AJ Mably, T O’Malley, SA Purro, C Terry, ... Nature communications 5 (1), 3374, 2014 | 200 | 2014 |
Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo K An, I Klyubin, Y Kim, JH Jung, AJ Mably, ST O’Dowd, T Lynch, ... Molecular brain 6, 1-13, 2013 | 200 | 2013 |
Impairments in spatial representations and rhythmic coordination of place cells in the 3xTg mouse model of Alzheimer's disease AJ Mably, BJ Gereke, DT Jones, LL Colgin Hippocampus 27 (4), 378-392, 2017 | 104 | 2017 |
Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity I Klyubin, AJ Nicoll, A Khalili-Shirazi, M Farmer, S Canning, A Mably, ... Journal of Neuroscience 34 (18), 6140-6145, 2014 | 88 | 2014 |
Cellular prion protein mediates the disruption of hippocampal synaptic plasticity by soluble tau in vivo T Ondrejcak, I Klyubin, GT Corbett, G Fraser, W Hong, AJ Mably, ... Journal of Neuroscience 38 (50), 10595-10606, 2018 | 87 | 2018 |
Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation GG Borlikova, M Trejo, AJ Mably, JM Mc Donald, CS Frigerio, CM Regan, ... Neurobiology of aging 34 (5), 1315-1327, 2013 | 87 | 2013 |
The aqueous phase of Alzheimer's disease brain contains assemblies built from∼ 4 and∼ 7 kDa Aβ species JM Mc Donald, TT O'Malley, W Liu, AJ Mably, G Brinkmalm, E Portelius, ... Alzheimer's & Dementia 11 (11), 1286-1305, 2015 | 58 | 2015 |
Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice AJ Mably, W Liu, JM Mc Donald, JC Dodart, F Bard, CA Lemere, ... Neurobiology of disease 82, 372-384, 2015 | 51 | 2015 |
A human monoclonal IgG that binds Aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo Y Levites, B O'Nuallain, RD Puligedda, T Ondrejcak, SP Adekar, C Chen, ... Journal of Neuroscience 35 (16), 6265-6276, 2015 | 35 | 2015 |
Tau immunization: a cautionary tale? AJ Mably, D Kanmert, JM Mc Donald, W Liu, BJ Caldarone, CA Lemere, ... Neurobiology of aging 36 (3), 1316-1332, 2015 | 33 | 2015 |
Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo I Klyubin, T Ondrejcak, J Hayes, WK Cullen, AJ Mably, DM Walsh, ... Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 32 | 2014 |
Peripheral interventions enhancing brain glutamate homeostasis relieve Amyloid β-and TNFα-mediated synaptic plasticity disruption in the Rat Hippocampus D Zhang, AJ Mably, DM Walsh, MJ Rowan Cerebral cortex 27 (7), 3724-3735, 2017 | 26 | 2017 |
Simvastatin treatment preserves synaptic plasticity in AβPPswe/PS1dE9 mice C Métais, K Brennan, AJ Mably, M Scott, DM Walsh, CE Herron Journal of Alzheimer's Disease 39 (2), 315-329, 2014 | 23 | 2014 |
Experience-dependent trends in CA1 theta and slow gamma rhythms in freely behaving mice BJ Gereke, AJ Mably, LL Colgin Journal of neurophysiology 119 (2), 476-489, 2018 | 21 | 2018 |
Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide AT Welzel, AD Williams, HP McWilliams-Koeppen, L Acero, A Weber, ... PLoS One 7 (11), e50317, 2012 | 17 | 2012 |
P4‐264: ARE ANTI‐ABETA AGGREGATE‐PREFERRING ANTIBODIES THE FUTURE FOR AD IMMUNOTHERAPY? B O'Nuallain, V Blinder, D Kanmert, T O'Malley, A Mably, J Frost, ... Alzheimer's & Dementia 10, P881-P882, 2014 | 2 | 2014 |
P4‐034: Alzheimer's disease human brain beta‐amyloid‐containing extracts inhibit hippocampal long‐term potentiation in rats in vivo: Relationship between … I Klyubin, A Mably, A Minogue, NW Hu, M Farrell, D Walsh, M Rowan Alzheimer's & Dementia 8 (4S_Part_18), P648-P648, 2012 | 2 | 2012 |
Experience-Dependent Trends in CA1 Theta and Slow Gamma Rhythms in Freely 1 JG Brian, AJ Mably, LL Colgin Hippocampus 27, 378-392, 2017 | | 2017 |