| An efficient one-step site-directed and site-saturation mutagenesis protocol L Zheng, U Baumann, JL Reymond Nucleic acids research 32 (14), e115-e115, 2004 | 1084 | 2004 |
| Enumeration of 166 billion organic small molecules in the chemical universe database GDB-17 L Ruddigkeit, R Van Deursen, LC Blum, JL Reymond Journal of chemical information and modeling 52 (11), 2864-2875, 2012 | 615 | 2012 |
| 970 million druglike small molecules for virtual screening in the chemical universe database GDB-13 LC Blum, JL Reymond Journal of the American Chemical Society 131 (25), 8732-8733, 2009 | 485 | 2009 |
| Multivalent glycoconjugates as anti-pathogenic agents A Bernardi, J Jiménez-Barbero, A Casnati, C De Castro, T Darbre, ... Chemical Society Reviews 42 (11), 4709-4727, 2013 | 434 | 2013 |
| Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems … T Fink, JL Reymond Journal of chemical information and modeling 47 (2), 342-353, 2007 | 386 | 2007 |
| Virtual exploration of the small‐molecule chemical universe below 160 daltons T Fink, H Bruggesser, JL Reymond Angewandte Chemie International Edition 44 (10), 1504-1508, 2005 | 297 | 2005 |
| The chemical space project JL Reymond Accounts of Chemical Research 48 (3), 722-730, 2015 | 293 | 2015 |
| Enzyme assays for high-throughput screening JP Goddard, JL Reymond Current opinion in biotechnology 15 (4), 314-322, 2004 | 290 | 2004 |
| Peptide dendrimers as artificial enzymes, receptors, and drug-delivery agents T Darbre, JL Reymond Accounts of chemical research 39 (12), 925-934, 2006 | 255 | 2006 |
| Novel methods for biocatalyst screening D Wahler, JL Reymond Current opinion in chemical biology 5 (2), 152-158, 2001 | 254 | 2001 |
| Chemical space as a source for new drugs JL Reymond, R Van Deursen, LC Blum, L Ruddigkeit MedChemComm 1 (1), 30-38, 2010 | 241 | 2010 |
| Recent advances in enzyme assays JP Goddard, JL Reymond TRENDS in Biotechnology 22 (7), 363-370, 2004 | 239 | 2004 |
| Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB EMV Johansson, SA Crusz, E Kolomiets, L Buts, RU Kadam, M Cacciarini, ... Chemistry & biology 15 (12), 1249-1257, 2008 | 223 | 2008 |
| Isolation and biochemical characterization of two novel metagenome-derived esterases C Elend, C Schmeisser, C Leggewie, P Babiak, JD Carballeira, HL Steele, ... Applied and environmental microbiology 72 (5), 3637-3645, 2006 | 203 | 2006 |
| Exploring chemical space for drug discovery using the chemical universe database JL Reymond, M Awale ACS chemical neuroscience 3 (9), 649-657, 2012 | 194 | 2012 |
| High-throughput screening for biocatalysts D Wahler, JL Reymond Current Opinion in Biotechnology 12 (6), 535-544, 2001 | 192 | 2001 |
| Dendrimers as artificial enzymes J Kofoed, JL Reymond Current opinion in chemical biology 9 (6), 656-664, 2005 | 183 | 2005 |
| Structure and mechanism of an active lipid-linked oligosaccharide flippase C Perez, S Gerber, J Boilevin, M Bucher, T Darbre, M Aebi, JL Reymond, ... Nature 524 (7566), 433-438, 2015 | 166 | 2015 |
| A strong positive dendritic effect in a peptide dendrimer-catalyzed ester hydrolysis reaction E Delort, T Darbre, JL Reymond Journal of the American Chemical Society 126 (48), 15642-15643, 2004 | 162 | 2004 |
| Discovery of new peptide-based catalysts for the direct asymmetric aldol reaction J Kofoed, J Nielsen, JL Reymond Bioorganic & medicinal chemistry letters 13 (15), 2445-2447, 2003 | 156 | 2003 |
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