Takip et
James Nettles
James Nettles
emory.edu üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Drugs that target dynamic microtubules: a new molecular perspective
RA Stanton, KM Gernert, JH Nettles, R Aneja
Medicinal research reviews 31 (3), 443-481, 2011
5722011
The binding mode of epothilone A on α, ß-tubulin by electron crystallography
JH Nettles, H Li, B Cornett, JM Krahn, JP Snyder, KH Downing
Science 305 (5685), 866-869, 2004
5282004
The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density
JP Snyder, JH Nettles, B Cornett, KH Downing, E Nogales
Proceedings of the National Academy of Sciences 98 (9), 5312-5316, 2001
5092001
Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition
DA Judd, JH Nettles, N Nevins, JP Snyder, DC Liotta, J Tang, J Ermolieff, ...
Journal of the American Chemical Society 123 (5), 886-897, 2001
4402001
Microtubule-interacting drugs for cancer treatment
PM Checchi, JH Nettles, J Zhou, JP Snyder, HC Joshi
Trends in pharmacological sciences 24 (7), 361-365, 2003
2402003
Bridging chemical and biological space:“target fishing” using 2D and 3D molecular descriptors
JH Nettles, JL Jenkins, A Bender, Z Deng, JW Davies, M Glick
Journal of medicinal chemistry 49 (23), 6802-6810, 2006
2202006
Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules
M Hari, F Loganzo, T Annable, X Tan, S Musto, DB Morilla, JH Nettles, ...
Molecular cancer therapeutics 5 (2), 270-278, 2006
2012006
Enrichment of high-throughput screening data with increasing levels of noise using support vector machines, recursive partitioning, and laplacian-modified naive bayesian …
M Glick, JL Jenkins, JH Nettles, H Hitchings, JW Davies
Journal of chemical information and modeling 46 (1), 193-200, 2006
1372006
“Bayes affinity fingerprints” improve retrieval rates in virtual screening and define orthogonal bioactivity space: when are multitarget drugs a feasible concept?
A Bender, JL Jenkins, M Glick, Z Deng, JH Nettles, JW Davies
Journal of chemical information and modeling 46 (6), 2445-2456, 2006
1292006
The oxetane ring in taxol
M Wang, B Cornett, J Nettles, DC Liotta, JP Snyder
The Journal of organic chemistry 65 (4), 1059-1068, 2000
1212000
Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones
S Ducki, G Mackenzie, B Greedy, S Armitage, JFD Chabert, E Bennett, ...
Bioorganic & medicinal chemistry 17 (22), 7711-7722, 2009
1132009
Massage therapy decreases cancer-related fatigue: Results from a randomized early phase trial
RMH Kinkead B, Schettler PJ, Larson ER, Carroll D, Sharenko M, Nettles J ...
Cancer 124 (3), 546-554, 2018
1112018
Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function
K Schafer-Hales, J Iaconelli, JP Snyder, A Prussia, JH Nettles, ...
Molecular cancer therapeutics 6 (4), 1317-1328, 2007
842007
Approaches to hepatitis C treatment and cure using NS5A inhibitors
JJ Kohler, JH Nettles, F Amblard, SJ Hurwitz, L Bassit, RA Stanton, ...
Infection and drug resistance, 41-56, 2014
832014
Understanding false positives in reporter gene assays: in silico chemogenomics approaches to prioritize cell-based HTS data
TJ Crisman, CN Parker, JL Jenkins, J Scheiber, M Thoma, ZB Kang, ...
Journal of chemical information and modeling 47 (4), 1319-1327, 2007
772007
Rational design of the microtubule-targeting anti–breast cancer drug EM015
R Aneja, M Lopus, J Zhou, SN Vangapandu, A Ghaleb, J Yao, JH Nettles, ...
Cancer research 66 (7), 3782-3791, 2006
712006
Asymmetric Binding to NS5A by Daclatasvir (BMS-790052) and Analogs Suggests Two Novel Modes of HCV Inhibition
JH Nettles, RA Stanton, J Broyde, F Amblard, H Zhang, L Zhou, J Shi, ...
American Chemical Society, 2014
542014
Flexible 3D pharmacophores as descriptors of dynamic biological space
JH Nettles, JL Jenkins, C Williams, AM Clark, A Bender, Z Deng, ...
Journal of Molecular Graphics and Modelling 26 (3), 622-633, 2007
532007
Substrates and Inhibitors of SAMHD1
JA Hollenbaugh, J Shelton, S Tao, S Amiralaei, P Liu, X Lu, RW Goetze, ...
PloS one 12 (1), e0169052, 2017
502017
“Plate cherry picking”: a novel semi-sequential screening paradigm for cheaper, faster, information-rich compound selection
TJ Crisman, JL Jenkins, CN Parker, WAG Hill, A Bender, Z Deng, ...
SLAS Discovery 12 (3), 320-327, 2007
372007
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