Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1 E Vacchelli, Y Ma, EE Baracco, A Sistigu, DP Enot, F Pietrocola, H Yang, ... Science 350 (6263), 972-978, 2015 | 433 | 2015 |
Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme R Pallini, L Ricci-Vitiani, GL Banna, M Signore, D Lombardi, M Todaro, ... Clinical Cancer Research 14 (24), 8205-8212, 2008 | 421 | 2008 |
Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy M Bartucci, S Svensson, P Romania, R Dattilo, M Patrizii, M Signore, ... Cell Death & Differentiation 19 (5), 768-778, 2012 | 201 | 2012 |
Targeting apoptosis pathways in cancer stem cells M Signore, L Ricci-Vitiani, R De Maria Cancer letters 332 (2), 374-382, 2013 | 149 | 2013 |
Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells L Lugini, M Valtieri, C Federici, S Cecchetti, S Meschini, M Condello, ... Oncotarget 7 (31), 50086, 2016 | 142 | 2016 |
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases L Grassi, R Alfonsi, F Francescangeli, M Signore, ML De Angelis, ... Cell death & disease 10 (3), 201, 2019 | 122 | 2019 |
Mesenchymal differentiation of glioblastoma stem cells L Ricci-Vitiani, R Pallini, LM Larocca, DG Lombardi, M Signore, ... Cell Death & Differentiation 15 (9), 1491-1498, 2008 | 116 | 2008 |
Heat shock proteins and their role in heart injury G Delogu, M Signore, A Mechelli, G Famularo Current opinion in critical care 8 (5), 411-416, 2002 | 114 | 2002 |
Integrin α7 is a functional marker and potential therapeutic target in glioblastoma TL Haas, MR Sciuto, L Brunetto, C Valvo, M Signore, ME Fiori, ... Cell stem cell 21 (1), 35-50. e9, 2017 | 112 | 2017 |
Chemotherapy-induced thrombocytopenia derives from the selective death of megakaryocyte progenitors and can be rescued by stem cell factor A Zeuner, M Signore, D Martinetti, M Bartucci, C Peschle, R De Maria Cancer research 67 (10), 4767-4773, 2007 | 101 | 2007 |
Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction A Eramo, R Pallini, F Lotti, G Sette, M Patti, M Bartucci, L Ricci-Vitiani, ... Cancer research 65 (24), 11469-11477, 2005 | 100 | 2005 |
Metabolic/proteomic signature defines two glioblastoma subtypes with different clinical outcome G Marziali, M Signore, M Buccarelli, S Grande, A Palma, M Biffoni, A Rosi, ... Scientific reports 6 (1), 21557, 2016 | 96 | 2016 |
Reverse-phase protein microarrays: application to biomarker discovery and translational medicine A VanMeter, M Signore, M Pierobon, V Espina, LA Liotta, EF Petricoin Iii Expert review of molecular diagnostics 7 (5), 625-633, 2007 | 92 | 2007 |
CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells G Manic, M Signore, A Sistigu, G Russo, F Corradi, S Siteni, M Musella, ... Gut 67 (5), 903-917, 2018 | 85 | 2018 |
Drug repurposing for the treatment of glioblastoma multiforme C Abbruzzese, S Matteoni, M Signore, L Cardone, K Nath, JD Glickson, ... Journal of Experimental & Clinical Cancer Research 36, 1-11, 2017 | 77 | 2017 |
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo M Signore, F Pelacchi, S Di Martino, D Runci, M Biffoni, S Giannetti, ... Cell death & disease 5 (5), e1223-e1223, 2014 | 76 | 2014 |
Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells M Bartucci, S Svensson, L Ricci-Vitiani, R Dattilo, M Biffoni, M Signore, ... Endocrine-related cancer 17 (3), 823-833, 2010 | 75 | 2010 |
Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1 S Notartomaso, C Zappulla, F Biagioni, M Cannella, D Bucci, G Mascio, ... Molecular brain 6, 1-17, 2013 | 72 | 2013 |
Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells A Zeuner, F Pedini, M Signore, G Ruscio, C Messina, A Tafuri, G Girelli, ... Blood 107 (9), 3495-3502, 2006 | 72 | 2006 |
A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer F Francescangeli, P Contavalli, ML De Angelis, S Careccia, M Signore, ... Journal of Experimental & Clinical Cancer Research 39, 1-17, 2020 | 71 | 2020 |