Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity P Zhang, F Sun, C Tsao, S Liu, P Jain, A Sinclair, HC Hung, T Bai, K Wu, ... Proceedings of the National Academy of Sciences 112 (39), 12046-12051, 2015 | 277 | 2015 |
Revealing the immunogenic risk of polymers B Li, Z Yuan, HC Hung, J Ma, P Jain, C Tsao, J Xie, P Zhang, X Lin, K Wu, ... Angewandte Chemie International Edition 57 (42), 13873-13876, 2018 | 100 | 2018 |
High-strength and fibrous capsule–resistant zwitterionic elastomers D Dong, C Tsao, HC Hung, F Yao, C Tang, L Niu, J Ma, J MacArthur, ... Science advances 7 (1), eabc5442, 2021 | 86 | 2021 |
Polypeptides with high zwitterion density for safe and effective therapeutics P Zhang, P Jain, C Tsao, Z Yuan, W Li, B Li, K Wu, HC Hung, X Lin, ... Angewandte Chemie 130 (26), 7869-7873, 2018 | 83 | 2018 |
Zwitterionic nanocages overcome the efficacy loss of biologic drugs B Li, Z Yuan, P Zhang, A Sinclair, P Jain, K Wu, C Tsao, J Xie, HC Hung, ... Advanced Materials 30 (14), 1705728, 2018 | 75 | 2018 |
A Coating‐Free Nonfouling Polymeric Elastomer HC Hung, P Jain, P Zhang, F Sun, A Sinclair, T Bai, B Li, K Wu, C Tsao, ... Advanced Materials 29 (31), 1700617, 2017 | 70 | 2017 |
Nanoscavenger provides long-term prophylactic protection against nerve agents in rodents P Zhang, EJ Liu, C Tsao, SA Kasten, MV Boeri, TL Dao, SJ DeBus, ... Science translational medicine 11 (473), eaau7091, 2019 | 58 | 2019 |
Butyrylcholinesterase nanocapsule as a long circulating bioscavenger with reduced immune response P Zhang, P Jain, C Tsao, A Sinclair, F Sun, HC Hung, T Bai, K Wu, S Jiang Journal of controlled release 230, 73-78, 2016 | 46 | 2016 |
Enhanced pulmonary systemic delivery of protein drugs via zwitterionic polymer conjugation C Tsao, Z Yuan, P Zhang, E Liu, P McMullen, K Wu, HC Hung, S Jiang Journal of controlled release 322, 170-176, 2020 | 29 | 2020 |
Zwitterionic polymer conjugated glucagon-like peptide-1 for prolonged glycemic control C Tsao, P Zhang, Z Yuan, D Dong, K Wu, L Niu, P McMullen, S Luozhong, ... Bioconjugate Chemistry 31 (7), 1812-1819, 2020 | 15 | 2020 |
Proactively Reducing Anti‐Drug Antibodies via Immunomodulatory Bioconjugation P Zhang, P Jain, C Tsao, K Wu, S Jiang Angewandte Chemie 131 (8), 2455-2458, 2019 | 15 | 2019 |
A low-immunogenic genetically-fusible zwitterionic polypeptide P McMullen, S Luozhong, C Tsao, H Xu, L Fang, S Jiang Nano Today 47, 101674, 2022 | 5 | 2022 |
Protein Encapsulation: Zwitterionic Nanocages Overcome the Efficacy Loss of Biologic Drugs (Adv. Mater. 14/2018) B Li, Z Yuan, P Zhang, A Sinclair, P Jain, K Wu, C Tsao, J Xie, HC Hung, ... Advanced Materials 30 (14), 1870101, 2018 | 1 | 2018 |
Fusion products and bioconjugates containing mixed charge peptides C Tsao, S Luozhong, T Corrigan, S Jiang, E Liu, P McMullen US Patent App. 17/283,708, 2021 | | 2021 |
Zwitteronic double network hydrogels S Jiang, HC Hung, D Dong, C Tsao, C Tang, J MacArthur US Patent App. 17/268,310, 2021 | | 2021 |
Zwitterionic Polymer-based Platforms for Biotherapeutics and Implants C Tsao University of Washington, 2020 | | 2020 |
Zwitterionic Polymeric Platforms for Biologic Drug Delivery and Tissue Engineering C Tsao, S Jiang 2019 AIChE Annual Meeting, 2019 | | 2019 |