Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases M Steger, F Tonelli, G Ito, P Davies, M Trost, M Vetter, S Wachter, ... elife 5, e12813, 2016 | 867 | 2016 |
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection JR Chapman, P Barral, JB Vannier, V Borel, M Steger, A Tomas-Loba, ... Molecular cell 49 (5), 858-871, 2013 | 730 | 2013 |
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis M Steger, F Diez, HS Dhekne, P Lis, RS Nirujogi, O Karayel, F Tonelli, ... elife 6, e31012, 2017 | 380 | 2017 |
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells IM Toller, KJ Neelsen, M Steger, ML Hartung, MO Hottiger, M Stucki, ... Proceedings of the National Academy of Sciences 108 (36), 14944-14949, 2011 | 344 | 2011 |
A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain HS Dhekne, I Yanatori, RC Gomez, F Tonelli, F Diez, B Schüle, M Steger, ... Elife 7, e40202, 2018 | 183 | 2018 |
DNA end resection by CtIP and exonuclease 1 prevents genomic instability W Eid, M Steger, M El‐Shemerly, LP Ferretti, J Peña‐Diaz, C König, ... EMBO reports 11 (12), 962-968, 2010 | 165 | 2010 |
MaxDIA enables library-based and library-free data-independent acquisition proteomics P Sinitcyn, H Hamzeiy, F Salinas Soto, D Itzhak, F McCarthy, C Wichmann, ... Nature biotechnology 39 (12), 1563-1573, 2021 | 137 | 2021 |
Organellar proteomics and phospho-proteomics reveal subcellular reorganization in diet-induced hepatic steatosis N Krahmer, B Najafi, F Schueder, F Quagliarini, M Steger, S Seitz, ... Developmental cell 47 (2), 205-221. e7, 2018 | 134 | 2018 |
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase P Lis, S Burel, M Steger, M Mann, F Brown, F Diez, F Tonelli, JL Holton, ... Biochemical Journal 475 (1), 1-22, 2018 | 127 | 2018 |
Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection M Steger, O Murina, D Hühn, LP Ferretti, R Walser, K Hänggi, L Lafranchi, ... Molecular cell 50 (3), 333-343, 2013 | 100 | 2013 |
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3β/β-catenin signaling S Trazzi, M Steger, VM Mitrugno, R Bartesaghi, E Ciani Journal of biological chemistry 285 (13), 10098-10109, 2010 | 90 | 2010 |
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism M Sakaguchi, W Cai, CH Wang, CT Cederquist, M Damasio, EP Homan, ... Nature Communications 10 (1), 1582, 2019 | 72 | 2019 |
Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale M Steger, V Demichev, M Backman, U Ohmayer, P Ihmor, S Müller, ... Nature communications 12 (1), 5399, 2021 | 71 | 2021 |
Accurate MS-based Rab10 phosphorylation stoichiometry determination as readout for LRRK2 activity in Parkinson's disease Ö Karayel, F Tonelli, SV Winter, PE Geyer, Y Fan, EM Sammler, DR Alessi, ... Molecular & Cellular Proteomics 19 (9), 1546-1560, 2020 | 60 | 2020 |
The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING–IFN-β pathway M Takahashi, CWJ Lio, A Campeau, M Steger, F Ay, M Mann, ... Nature immunology 22 (4), 485-496, 2021 | 58 | 2021 |
Distinct signaling by insulin and IGF-1 receptors and their extra-and intracellular domains H Nagao, W Cai, NJ Wewer Albrechtsen, M Steger, TM Batista, H Pan, ... Proceedings of the National Academy of Sciences 118 (17), e2019474118, 2021 | 46 | 2021 |
Phosphoproteomics reveals that Parkinson’s disease kinase LRRK2 regulates a subset of Rab GTPases. eLife 5 M Steger, F Tonelli, G Ito, P Davies, M Trost, M Vetter, S Wachter, ... JANUARY2016, 2016 | 39 | 2016 |
Robust dimethyl‐based multiplex‐DIA doubles single‐cell proteome depth via a reference channel M Thielert, ECM Itang, C Ammar, FA Rosenberger, I Bludau, L Schweizer, ... Molecular Systems Biology 19 (9), e11503, 2023 | 25* | 2023 |
The natural diversity of the yeast proteome reveals chromosome-wide dosage compensation in aneuploids J Muenzner, P Trébulle, F Agostini, CB Messner, M Steger, A Lehmann, ... BioRxiv, 2022.04. 06.487392, 2022 | 20 | 2022 |
Fam20C regulates protein secretion by Cab45 phosphorylation TKH Hecht, B Blank, M Steger, V Lopez, G Beck, B Ramazanov, M Mann, ... Journal of Cell Biology 219 (6), e201910089, 2020 | 18 | 2020 |