| A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene. J Perez-Tur, S Froelich, G Prihar, R Crook, M Baker, K Duff, M Wragg, ... Neuroreport 7 (1), 297-301, 1995 | 357 | 1995 |
| Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease M Wragg, C Talbot, M Hutton, A Goate, ... The Lancet 347 (9000), 509-512, 1996 | 276 | 1996 |
| Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease. M Hutton, F Busfield, M Wragg, R Crook, J Perez-Tur, RF Clark, G Prihar, ... Neuroreport 7 (3), 801-805, 1996 | 221 | 1996 |
| The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families RF Clark, M Hutton, M Fuldner, S Froelich, E Karran, C Talbot, R Crook, ... Nature genetics 11 (2), 219-222, 1995 | 219 | 1995 |
| Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice RL Nelson, Z Guo, VM Halagappa, M Pearson, AJ Gray, Y Matsuoka, ... Experimental neurology 205 (1), 166-176, 2007 | 200 | 2007 |
| Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity WS Saunders, C Chue, M Goebl, C Craig, RF Clark, JA Powers, ... Journal of Cell Science 104 (2), 573-582, 1993 | 192 | 1993 |
| LungMAP: The molecular atlas of lung development program ME Ardini-Poleske, RF Clark, C Ansong, JP Carson, RA Corley, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (5 …, 2017 | 173 | 2017 |
| Molecular genetics of Alzheimer's disease RF Clark, AM Goate Archives of neurology 50 (11), 1164-1172, 1993 | 172 | 1993 |
| Chromosome 14–encoded Alzheimer's disease: genetic and clinicopathological description M Haltia, M Viitanen, R Sulkava, V Ala‐Hurula, M Poyhonen, L Goldfarb, ... Annals of Neurology: Official Journal of the American Neurological …, 1994 | 110 | 1994 |
| Structure and alternative splicing of the presenilin-2 gene. G Prihar, RA Fuldner, J Perez-Tur, S Lincoln, K Duff, R Crook, J Hardy, ... Neuroreport 7 (10), 1680-1684, 1996 | 69 | 1996 |
| Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved in Drosophila RF Clark, SCR Elgin Nucleic acids research 20 (22), 6067-6074, 1992 | 51 | 1992 |
| Fractionation of human H1 subtypes and characterization of a subtype-specific antibody exhibiting non-uniform nuclear staining MH Parseghian, RF Clark, LJ Hauser, N Dvorkin, DA Harris, BA Hamkalo Chromosome Research 1, 127-139, 1993 | 48 | 1993 |
| Genetic and physical characterization of the early-onset Alzheimer's disease AD3 locus on chromosome 14q24.3 M Cruts, H Backhovens, J Theuns, RF Clark, D Le Paslier, J Weissenbach, ... Human molecular genetics 4 (8), 1355-1364, 1995 | 45 | 1995 |
| Metabolomics analysis of hormone-responsive and triple-negative breast cancer cell responses to paclitaxel identify key metabolic differences DA Stewart, JH Winnike, SL McRitchie, RF Clark, WW Pathmasiri, ... Journal of Proteome Research 15 (9), 3225-3240, 2016 | 44 | 2016 |
| Posttranslational modification and plasma membrane localization of the Drosophila melanogaster presenilin P Nowotny, SM Gorski, SW Han, K Philips, WJ Ray, V Nowotny, CJ Jones, ... Molecular and Cellular Neuroscience 15 (1), 88-98, 2000 | 43 | 2000 |
| A yeast artificial chromosome contig from human chromosome 14q24 spanning the Alzheimer's disease locus AD3 RF Clark, M Cruts, KM Korenblat, C He, C Talbot, C Van Broeckhoven, ... Human molecular genetics 4 (8), 1347-1354, 1995 | 31 | 1995 |
| Omics technologies used in systems biology D Stewart, S Dhungana, R Clark, W Pathmasiri, S McRitchie, S Sumner Systems Biology in Toxicology and Environmental Health, 57, 2015 | 22 | 2015 |
| The role of presenilin 1 in the genetics of Alzheimer's disease RF Clark, M Hutton, C Talbot, M Wragg, C Lendon, F Busfield, SW Han, ... Cold Spring Harbor symposia on quantitative biology 61, 551-558, 1996 | 19 | 1996 |
| Preferential distribution of active RNA polymerase II molecules in the nuclear periphery. RF Clark, KW Cho, R Weinmann, BA Hamkalo Gene expression 1 (1), 61-70, 1991 | 18 | 1991 |
| Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease AJL Barton, BW Crook, EH Karran, F Brown, D Dewar, DMA Mann, ... Neurodegeneration 5 (3), 213-218, 1996 | 17 | 1996 |
Alison GoateProfessor of Genetics & Genomic Sciences, Icahn School of Medicine at Mount SinaiVerified email at mssm.edu
