Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2435 | 2014 |
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2433 | 2014 |
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ... Nature 537 (7621), 544-547, 2016 | 518 | 2016 |
The stem cell secretome and its role in brain repair D Drago, C Cossetti, N Iraci, E Gaude, G Musco, A Bachi, S Pluchino Biochimie 95 (12), 2271-2285, 2013 | 414 | 2013 |
Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities EM Kerr, E Gaude, FK Turrell, C Frezza, CP Martins Nature 531 (7592), 110-113, 2016 | 313 | 2016 |
Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival E Gaude, C Frezza Nature communications 7 (1), 13041, 2016 | 308 | 2016 |
Defects in mitochondrial metabolism and cancer E Gaude, C Frezza Cancer & metabolism 2, 1-9, 2014 | 275 | 2014 |
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo PA Gammage, C Viscomi, ML Simard, ASH Costa, E Gaude, CA Powell, ... Nature medicine 24 (11), 1691-1695, 2018 | 265 | 2018 |
Fumarate induces redox-dependent senescence by modifying glutathione metabolism L Zheng, S Cardaci, L Jerby, ED MacKenzie, M Sciacovelli, TI Johnson, ... Nature communications 6 (1), 6001, 2015 | 263 | 2015 |
NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction E Gaude, C Schmidt, PA Gammage, A Dugourd, T Blacker, SP Chew, ... Molecular cell 69 (4), 581-593. e7, 2018 | 214 | 2018 |
Germline FH Mutations Presenting With Pheochromocytoma GR Clark, M Sciacovelli, E Gaude, DM Walsh, G Kirby, MA Simpson, ... The Journal of Clinical Endocrinology & Metabolism 99 (10), E2046-E2050, 2014 | 181 | 2014 |
A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients D Rodenhizer, E Gaude, D Cojocari, R Mahadevan, C Frezza, ... Nature materials 15 (2), 227-234, 2016 | 144 | 2016 |
Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer K Yizhak, E Gaude, S Le Dévédec, YY Waldman, GY Stein, ... Elife 3, e03641, 2014 | 140 | 2014 |
Safety and efficacy of transcranial direct current stimulation in acute experimental ischemic stroke L Peruzzotti-Jametti, M Cambiaghi, M Bacigaluppi, M Gallizioli, E Gaude, ... Stroke 44 (11), 3166-3174, 2013 | 135 | 2013 |
Extracellular vesicles are independent metabolic units with asparaginase activity N Iraci, E Gaude, T Leonardi, ASH Costa, C Cossetti, L Peruzzotti-Jametti, ... Nature chemical biology 13 (9), 951-955, 2017 | 128 | 2017 |
Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death D Catanzaro, E Gaude, G Orso, C Giordano, G Guzzo, A Rasola, ... Oncotarget 6 (30), 30102, 2015 | 122 | 2015 |
Integrated pharmacodynamic analysis identifies two metabolic adaption pathways to metformin in breast cancer SR Lord, WC Cheng, D Liu, E Gaude, S Haider, T Metcalf, N Patel, ... Cell metabolism 28 (5), 679-688. e4, 2018 | 121 | 2018 |
The metabolic alterations of cancer cells M Sciacovelli, E Gaude, M Hilvo, C Frezza Methods in enzymology 542, 1-23, 2014 | 121 | 2014 |
Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs PA Gammage, E Gaude, L Van Haute, P Rebelo-Guiomar, CB Jackson, ... Nucleic acids research 44 (16), 7804-7816, 2016 | 117 | 2016 |
muma, an R package for metabolomics univariate and multivariate statistical analysis E Gaude, F Chignola, D Spiliotopoulos, A Spitaleri, M Ghitti, ... Current Metabolomics 1 (2), 180-189, 2013 | 107 | 2013 |