de Sauvage
de Sauvage
Frederic
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Alıntı yapanlar
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Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
S Aggarwal, N Ghilardi, MH Xie, FJ de Sauvage, AL Gurney
Journal of Biological Chemistry 278 (3), 1910-1914, 2003
22532003
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
Y Zheng, PA Valdez, DM Danilenko, Y Hu, SM Sa, Q Gong, AR Abbas, ...
Nature medicine 14 (3), 282-289, 2008
17812008
Influence of tumour micro-environment heterogeneity on therapeutic response
MR Junttila, FJ De Sauvage
Nature 501 (7467), 346-354, 2013
17052013
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
FJ De Sauvage, PE Hass, SD Spencer, BE Malloy, AL Gurney, ...
Nature 369 (6481), 533-538, 1994
16191994
Activating Smoothened mutations in sporadic basal-cell carcinoma
J Xie, M Murone, SM Luoh, A Ryan, Q Gu, C Zhang, JM Bonifas, CW Lam, ...
Nature 391 (6662), 90-92, 1998
14101998
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
DM Stone, M Hynes, M Armanini, TA Swanson, Q Gu, RL Johnson, ...
Nature 384 (6605), 129-134, 1996
12641996
Characterization of a multicomponent receptor for GDNF
JJS Treanor, L Goodman, F de Sauvage, DM Stone, KT Poulsen, ...
Nature 382 (6586), 80-83, 1996
12011996
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma
DD Von Hoff, PM LoRusso, CM Rudin, JC Reddy, RL Yauch, R Tibes, ...
New England Journal of Medicine 361 (12), 1164-1172, 2009
11792009
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
J Ridgway, G Zhang, Y Wu, S Stawicki, WC Liang, Y Chanthery, ...
Nature 444 (7122), 1083-1087, 2006
10602006
Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
CM Rudin, CL Hann, J Laterra, RL Yauch, CA Callahan, L Fu, T Holcomb, ...
New England Journal of Medicine 361 (12), 1173-1178, 2009
10552009
A paracrine requirement for hedgehog signalling in cancer
RL Yauch, SE Gould, SJ Scales, T Tang, H Tian, CP Ahn, D Marshall, ...
Nature 455 (7211), 406-410, 2008
10552008
Diverse somatic mutation patterns and pathway alterations in human cancers
Z Kan, BS Jaiswal, J Stinson, V Janakiraman, D Bhatt, HM Stern, P Yue, ...
Nature 466 (7308), 869-873, 2010
9952010
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
H Tian, B Biehs, S Warming, KG Leong, L Rangell, OD Klein, ...
Nature 478 (7368), 255-259, 2011
9762011
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells
M Batten, J Li, S Yi, NM Kljavin, DM Danilenko, S Lucas, J Lee, ...
Nature immunology 7 (9), 929-936, 2006
9592006
Targeting the Hedgehog pathway in cancer
LL Rubin, FJ de Sauvage
Nature reviews Drug discovery 5 (12), 1026-1033, 2006
8662006
Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma
RL Yauch, GJP Dijkgraaf, B Alicke, T Januario, CP Ahn, T Holcomb, ...
Science 326 (5952), 572-574, 2009
8502009
Recurrent R-spondin fusions in colon cancer
S Seshagiri, EW Stawiski, S Durinck, Z Modrusan, EE Storm, CB Conboy, ...
Nature 488 (7413), 660-664, 2012
8312012
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
ST Avecilla, K Hattori, B Heissig, R Tejada, F Liao, K Shido, DK Jin, ...
Nature medicine 10 (1), 64-71, 2004
8302004
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
CM Rudin, S Durinck, EW Stawiski, JT Poirier, Z Modrusan, DS Shames, ...
Nature genetics 44 (10), 1111-1116, 2012
7762012
Thrombocytopenia in c-mpl-deficient mice
AL Gurney, K Carver-Moore, FJ de Sauvage, MW Moore
Science 265 (5177), 1445-1447, 1994
7351994
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