Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps NS Nemeria, S Chakraborty, A Balakrishnan, F Jordan The FEBS journal 276 (9), 2432-3446, 2009 | 2296 | 2009 |
Para-Aminosalicylic Acid Acts as an Alternative Substrate of Folate Metabolism in Mycobacterium tuberculosis S Chakraborty, T Gruber, CE Barry III, HI Boshoff, KY Rhee Science 339 (6115), 88-91, 2013 | 228 | 2013 |
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence JH Kim, KM O’Brien, R Sharma, HIM Boshoff, G Rehren, S Chakraborty, ... Proceedings of the National Academy of Sciences 110 (47), 19095-19100, 2013 | 143 | 2013 |
Tuberculosis drug development: history and evolution of the mechanism-based paradigm S Chakraborty, KY Rhee Cold Spring Harbor perspectives in medicine 5 (8), a021147, 2015 | 115 | 2015 |
The 1′, 4′-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes N Nemeria, S Chakraborty, A Baykal, LG Korotchkina, MS Patel, F Jordan Proceedings of the National Academy of Sciences 104 (1), 78-82, 2007 | 100 | 2007 |
Synthesis with good enantiomeric excess of both enantiomers of α-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases A Baykal, S Chakraborty, A Dodoo, F Jordan Bioorganic chemistry 34 (6), 380-393, 2006 | 50 | 2006 |
Determination of pre-steady-state rate constants on the Escherichia coli pyruvate dehydrogenase complex reveals that loop movement controls the rate-limiting step A Balakrishnan, NS Nemeria, S Chakraborty, L Kakalis, F Jordan Journal of the American Chemical Society 134 (45), 18644-18655, 2012 | 46 | 2012 |
Acetylphosphinate is the most potent mechanism-based substrate-like inhibitor of both the human and Escherichia coli pyruvate dehydrogenase components of the pyruvate … NS Nemeria, LG Korotchkina, S Chakraborty, MS Patel, F Jordan Bioorganic chemistry 34 (6), 362-379, 2006 | 45 | 2006 |
Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester GS Brandt, N Nemeria, S Chakraborty, MJ McLeish, A Yep, GL Kenyon, ... Biochemistry 47 (29), 7734-7743, 2008 | 40 | 2008 |
Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor GS Brandt, MM Kneen, S Chakraborty, AT Baykal, N Nemeria, A Yep, ... Biochemistry 48 (15), 3247-3257, 2009 | 37 | 2009 |
Solid-state nuclear magnetic resonance studies delineate the role of the protein in activation of both aromatic rings of thiamin A Balakrishnan, S Paramasivam, S Chakraborty, T Polenova, F Jordan Journal of the American Chemical Society 134 (1), 665-672, 2012 | 35 | 2012 |
Evolution of a thienopyrimidine antitubercular relying on medicinal chemistry and metabolomics insights SG Li, C Vilchèze, S Chakraborty, X Wang, H Kim, M Anisetti, S Ekins, ... Tetrahedron letters 56 (23), 3246-3250, 2015 | 30 | 2015 |
Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects S Chakraborty, N Nemeria, A Yep, MJ McLeish, GL Kenyon, F Jordan Biochemistry 47 (12), 3800-3809, 2008 | 26 | 2008 |
Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase S Chakraborty, NS Nemeria, A Balakrishnan, GS Brandt, MM Kneen, ... Biochemistry 48 (5), 981-994, 2009 | 22 | 2009 |
Detection of covalent and noncovalent intermediates in the polymerization reaction catalyzed by a C149S class III polyhydroxybutyrate synthase P Li, S Chakraborty, JA Stubbe Biochemistry 48 (39), 9202-9211, 2009 | 20 | 2009 |
Monitoring bound HA1 (H1N1) and HA1 (H5N1) on freely suspended graphene over plasmonic platforms with infrared spectroscopy A Banerjee, S Chakraborty, N Altan-Bonnet, H Grebel Chemical Physics Letters 582, 134-140, 2013 | 1 | 2013 |
Use of thiamin diphosphate‐dependent decarboxylases in chiral synthesis of carboligase products AT Baykal, S Chakraborty, N Nemeria, F Jordan The FASEB Journal 20 (4), A40-A40, 2006 | 1 | 2006 |
Electron-Acoustic Solitary waves in Fermi Plasma with Two-Temperature Electrons A Dey, S Pramanick, S Chakraborty, M Sarkar, S Chandra Jointly Organised by, 34, 2020 | | 2020 |
Metabolomics-aided optimization of antitubercular thienopyrimidines SG Li, C Vilcheze, S Chakraborty, X Wang, H Kim, M Anisetti, S Ekins, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
Infrared detection of flu viruses A Banerjee, S Chakraborty, H Grebel IEEE Photonics Conference 2012, 153-154, 2012 | | 2012 |