Membrane oxidation in cell delivery and cell killing applications TY Wang, MDJ Libardo, AM Angeles-Boza, JP Pellois ACS chemical biology 12 (5), 1170-1182, 2017 | 129 | 2017 |
Nuclease activity gives an edge to host‐defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms MDJ Libardo, AA Bahar, B Ma, R Fu, LE McCormick, J Zhao, ... The FEBS journal 284 (21), 3662-3683, 2017 | 110 | 2017 |
The present state of the tuberculosis drug development pipeline MDJ Libardo, HIM Boshoff, CE Barry III Current opinion in pharmacology 42, 81-94, 2018 | 84 | 2018 |
Improved Bioactivity of Antimicrobial Peptides by Addition of Amino‐Terminal Copper and Nickel (ATCUN) Binding Motifs MD Libardo, JL Cervantes, JC Salazar, AM Angeles‐Boza ChemMedChem 9 (8), 1892-1901, 2014 | 69 | 2014 |
Antimicrobial peptides and copper (II) ions: Novel therapeutic opportunities J Portelinha, SS Duay, SI Yu, K Heilemann, MDJ Libardo, SA Juliano, ... Chemical reviews 121 (4), 2648-2712, 2021 | 64 | 2021 |
Copper-binding tripeptide motif increases potency of the antimicrobial peptide Anoplin via Reactive Oxygen Species generation MDJ Libardo, S Nagella, A Lugo, S Pierce, AM Angeles-Boza Biochemical and Biophysical Research Communications 456 (1), 446-451, 2015 | 58 | 2015 |
Complementary effects of host defense peptides piscidin 1 and piscidin 3 on DNA and lipid membranes: biophysical insights into contrasting biological activities RM Hayden, GK Goldberg, BM Ferguson, MW Schoeneck, MDJ Libardo, ... The journal of physical chemistry B 119 (49), 15235-15246, 2015 | 54 | 2015 |
Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches AJ Whitehouse, SE Thomas, KP Brown, A Fanourakis, DSH Chan, ... Journal of Medicinal Chemistry 62 (15), 7210-7232, 2019 | 37 | 2019 |
Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity MDJ Libardo, TJ Paul, R Prabhakar, AM Angeles-Boza Biochimie 113, 143-155, 2015 | 37 | 2015 |
Central role of the copper-binding motif in the complex mechanism of action of ixosin: enhancing oxidative damage and promoting synergy with ixosin B MDJ Libardo, VY Gorbatyuk, AM Angeles-Boza ACS Infectious Diseases 2 (1), 71-81, 2016 | 36 | 2016 |
Phagosomal Copper-Promoted Oxidative Attack on Intracellular Mycobacterium tuberculosis MDJ Libardo, C de la Fuente-Nuñez, K Anand, G Krishnamoorthy, ... ACS infectious diseases 4 (11), 1623-1634, 2018 | 32 | 2018 |
How does membrane oxidation affect cell delivery and cell killing? MDJ Libardo, TY Wang, JP Pellois, AM Angeles-Boza Trends in biotechnology 35 (8), 686-690, 2017 | 28 | 2017 |
Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification SE Thomas, AJ Whitehouse, K Brown, S Burbaud, JM Belardinelli, ... Nucleic Acids Research 48 (14), 8099-8112, 2020 | 22 | 2020 |
Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption F Comert, F Heinrich, A Chowdhury, M Schoeneck, C Darling, ... Scientific reports 11 (1), 12620, 2021 | 12 | 2021 |
Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode AJ Whitehouse, MDJ Libardo, M Kasbekar, PD Brear, G Fischer, ... Journal of medicinal chemistry 62 (23), 10586-10604, 2019 | 12 | 2019 |
Bioinorganic chemistry of antimicrobial and host-defense peptides MDJ Libardo, AM Angeles-Boza Comments on Inorganic Chemistry 34 (1-2), 42-58, 2014 | 12 | 2014 |
Structure–Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents S Oh, MDJ Libardo, S Azeeza, GT Pauly, JSO Roma, A Sajid, Y Tateishi, ... ACS Infectious Diseases 7 (2), 479-492, 2021 | 11 | 2021 |
Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis MDJ Libardo, CJ Duncombe, SR Green, PG Wyatt, S Thompson, PC Ray, ... Cell Chemical Biology 28 (8), 1180-1191. e20, 2021 | 9 | 2021 |
Multifunctional nanocoatings from one-step co-assembly S Chavez, J Liu, MD Libardo, G Ducati, QM Dao, AA Boza, L Sun ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Cytotoxic property of Streptocaulon baumii extracts and their isolated compounds against different human cancer cell lines AP Bartolome, IM Villaseñor, YL Lin, MDJ Libardo, AM Angeles-Boza, ... Philippine Science Letters 10 (2), 89-97, 2017 | | 2017 |