PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis F Liu, F Ma, Y Wang, L Hao, H Zeng, C Jia, Y Wang, P Liu, IM Ong, B Li, ... Nature cell biology 19 (11), 1358-1370, 2017 | 224 | 2017 |
Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition E Shishkova, H Zeng, F Liu, NW Kwiecien, AS Hebert, JJ Coon, W Xu Nature communications 8 (1), 15571, 2017 | 116 | 2017 |
MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs L Wang, H Zeng, Q Wang, Z Zhao, TG Boyer, X Bian, W Xu Science advances 1 (9), e1500463, 2015 | 76 | 2015 |
mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level H Zeng, B Lu, R Zamponi, Z Yang, K Wetzel, J Loureiro, S Mohammadi, ... Proceedings of the National Academy of Sciences 115 (44), E10362-E10369, 2018 | 63 | 2018 |
Ctr9, a key subunit of PAFc, affects global estrogen signaling and drives ERα-positive breast tumorigenesis H Zeng, W Xu Genes & Development 29 (20), 2153-2167, 2015 | 42 | 2015 |
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC H Zeng, J Castillo-Cabrera, M Manser, B Lu, Z Yang, V Strande, D Begue, ... Elife 8, e50223, 2019 | 38 | 2019 |
A TR‐FRET‐Based Functional Assay for Screening Activators of CARM1 H Zeng, J Wu, MT Bedford, G Sbardella, FM Hoffmann, K Bi, W Xu Chembiochem 14 (7), 827-835, 2013 | 25 | 2013 |
Covalent ERα antagonist H3B-6545 demonstrates encouraging preclinical activity in therapy-resistant breast cancer C Furman, X Puyang, Z Zhang, ZJ Wu, D Banka, KB Aithal, LA Albacker, ... Molecular Cancer Therapeutics 21 (6), 890-902, 2022 | 13 | 2022 |
Enzymatic Assays of Histone Methyltransferase Enzymes H Zeng Epigenetic Technological Applications, Pages 333–361, 2015 | 10 | 2015 |
Identification of 2-sulfonyl/sulfonamide pyrimidines as covalent inhibitors of WRN using a multiplexed high-throughput screening assay MJ Parker, H Lee, S Yao, S Irwin, S Hwang, K Belanger, SW de Mare, ... Biochemistry 62 (14), 2147-2160, 2023 | 9 | 2023 |
Systematic identification of Ctr9 regulome in ERα-positive breast cancer H Zeng, L Lu, NT Chan, M Horswill, P Ahlquist, X Zhong, W Xu BMC genomics 17, 1-14, 2016 | 9 | 2016 |
The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium NT Chan, J Huang, G Ma, H Zeng, K Donahue, Y Wang, L Li, W Xu Nucleic Acids Research 50 (4), 1969-1992, 2022 | 5 | 2022 |
Gene expression profiling of Ctr9-regulated transcriptome in ERα-positive breast cancer H Zeng, W Xu Genomics Data 7, 103-104, 2016 | 5 | 2016 |
PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis (vol 19, pg 1358, 2017) F Liu, F Ma, Y Wang, L Hao, H Zeng, C Jia, Y Wang, P Liu, IM Ong, B Li, ... NATURE CELL BIOLOGY 19 (12), 1442-1442, 2017 | | 2017 |
Haploid genetic screens identify key regulators of protein phenotypes and signaling transduction H Zeng AME Medical Journal 2 (11), 2017 | | 2017 |
Abstract PR12: MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs W Lu, H Zeng, Q Wang, Z Zhao, TG Boyer, X Bian, W Xu Cancer Research 76 (2_Supplement), PR12-PR12, 2016 | | 2016 |
Epigenetic and transcriptional control in human breast cancer H Zeng The University of Wisconsin-Madison, 2015 | | 2015 |
Cover Picture: A TR‐FRET‐Based Functional Assay for Screening Activators of CARM1 (ChemBioChem 7/2013) H Zeng, J Wu, MT Bedford, G Sbardella, FM Hoffmann, K Bi, W Xu ChemBioChem 14 (7), 773-773, 2013 | | 2013 |