Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors G Eren, A Bruno, S Guntekin-Ergun, R Cetin-Atalay, F Ozgencil, Y Ozkan, ... Journal of Molecular Graphics and Modelling 89, 60-73, 2019 | 25 | 2019 |
Studies on the synthesis, characterization, cytotoxic activities and plasmid DNA binding of platinum (II) complexes having 2-subsituted benzimidazole ligands M Gozelle, AK Süloğlu, G Selmanoğlu, N Ramazanoğlu, L Açık, F Gümüş Polyhedron 161, 298-308, 2019 | 25 | 2019 |
Structure-based exploration and pharmacological evaluation of N-Substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists I Adlere, S Sun, A Zarca, L Roumen, M Gozelle, CP Viciano, B Caspar, ... European Journal of Medicinal Chemistry 162, 631-649, 2019 | 16 | 2019 |
Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT S Yagci, M Gozelle, SG Kaya, Y Ozkan, AB Aksel, F Bakar-Ates, Y Dundar, ... Bioorganic & Medicinal Chemistry 30, 115961, 2021 | 9 | 2021 |
Hit evaluation results in 5-benzyl-1, 3, 4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity M Gozelle, SG Kaya, AB Aksel, E Ozkan, F Bakar-Ates, Y Ozkan, G Eren Bioorganic Chemistry 123, 105746, 2022 | 7 | 2022 |
The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by … MK Sukuroglu, M Gozelle, Y Ozkan, G Eren Medicinal Chemistry Research 30 (10), 1915-1924, 2021 | 5 | 2021 |
In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual … M Gozelle, F Bakar-Ates, A Massarotti, E Ozkan, HB Gunindi, Y Ozkan, ... Journal of Biomolecular Structure and Dynamics, 1-12, 2023 | 4 | 2023 |
Linker and tail group modifications on 2-((4-isopropyl-4H-1, 2, 4-triazol-3-yl) thio)-N-(4-phenoxyphenyl) acetamide to improve SIRT2 inhibitory potency M Gozelle, Y Özkan, G Eren Fabad Journal of Pharmaceutical Sciences 49 (2), 317-332, 2024 | 1 | 2024 |
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition SG Kaya, G Eren, A Massarotti, F Bakar‐Ates, E Ozkan, M Gozelle, ... Drug development research 85 (4), e22224, 2024 | 1 | 2024 |
Synthesis, crystal structure, spectroscopic and density functional modelling studies of the 2-isopropylbenzimidazolium tetrachloroplatinate (II) monohydrate M Gozelle, CT Zeyrek, H Ünver, N Dilek, F Gümüş Gazi University Journal of Science 30 (1), 139-159, 2017 | 1 | 2017 |
Enzalutamide-human serum albumin interaction: Electrochemical exploration of complex formation and binding parameters F Chenguiti, NK Bakirhan, M Gozelle, M Doulache, B Saidat, EB Atici, ... Microchemical Journal 201, 110760, 2024 | | 2024 |
Synthesis of 2-Substitutedbenzimidazolium Tetrachloroplatinate (II) Compounds and Their Cytotoxic Activities on Different Cell Lines M Gözelle, AK Süloğlu Fabad Journal of Pharmaceutical Sciences 47 (3), 281-292, 2022 | | 2022 |