| Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance EE Bram, M Stark, S Raz, YG Assaraf Neoplasia 11 (12), 1359-IN11, 2009 | 152 | 2009 |
| Genetically programmable pathogen sense and destroy S Gupta, EE Bram, R Weiss ACS synthetic biology 2 (12), 715-723, 2013 | 144 | 2013 |
| Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin GL Beretta, V Benedetti, G Cossa, YGA Assaraf, E Bram, L Gatti, E Corna, ... Biochemical pharmacology 79 (8), 1108-1117, 2010 | 121 | 2010 |
| Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers Y Adar, M Stark, EE Bram, P Nowak-Sliwinska, H Van Den Bergh, ... Cell death & disease 3 (4), e293-e293, 2012 | 106 | 2012 |
| ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolates A Shafran, I Ifergan, E Bram, G Jansen, I Kathmann, GJ Peters, RW Robey, ... Cancer research 65 (18), 8414-8422, 2005 | 65 | 2005 |
| Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance M Stark, EE Bram, M Akerman, Y Mandel-Gutfreund, YG Assaraf Journal of biological chemistry 286 (5), 3741-3754, 2011 | 60 | 2011 |
| A Genotype-Phenotype Study of High-Resolution FMR1 Nucleic Acid and Protein Analyses in Fragile X Patients with Neurobehavioral Assessments DB Budimirovic, A Schlageter, S Filipovic-Sadic, DD Protic, E Bram, ... Brain sciences 10 (10), 694, 2020 | 58 | 2020 |
| C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells EE Bram, I Ifergan, M Grimberg, K Lemke, A Skladanowski, YG Assaraf Biochemical pharmacology 74 (1), 41-53, 2007 | 56 | 2007 |
| PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells N Gonen, EE Bram, YG Assaraf Biochemical and biophysical research communications 376 (4), 787-792, 2008 | 53 | 2008 |
| Mutant Gly482 and Thr482 ABCG2 mediate high-level resistance to lipophilic antifolates E Bram, I Ifergan, A Shafran, B Berman, G Jansen, YG Assaraf Cancer chemotherapy and pharmacology 58, 826-834, 2006 | 44 | 2006 |
| Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2 EE Bram, Y Adar, N Mesika, M Sabisz, A Skladanowski, YG Assaraf Molecular pharmacology 75 (5), 1149-1159, 2009 | 29 | 2009 |
| Comprehensive genotyping of the C9orf72 hexanucleotide repeat region in 2095 ALS samples from the NINDS collection using a two-mode, long-read PCR assay E Bram, K Javanmardi, K Nicholson, K Culp, JR Thibert, J Kemppainen, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (1-2), 107-114, 2019 | 12 | 2019 |
| Genetically programmable pathogen sense and destroy. ACS Synth Biol 2: 715–723 S Gupta, EE Bram, R Weiss | 5 | 2013 |
| Methods for nucleic acid size detection of repeat sequences E Bram, R Shroff, A Hadd, B Printy US Patent App. 15/343,057, 2017 | 3 | 2017 |
| Imidazoacridinone derivative compounds and methods for their use YG Assaraf, EE Bram, Y Bney-Moshe, AM Skladanowski US Patent 8,470,844, 2013 | 1 | 2013 |
| Methods for nucleic acid size detection of repeat sequences E Bram, R Shroff, A Hadd, B Printy US Patent 11,913,068, 2024 | | 2024 |
| Rapid and Accurate Quantification of Endonuclease Activity Using a Kinetic FRET Assay G Mineo, L Chamberlain, T Gyuris, E Bram, M Dodge JOURNAL OF MOLECULAR DIAGNOSTICS 25 (11), S155-S156, 2023 | | 2023 |
| Mitochondrial DNA as an Intrinsic Control for Enhancing MSRE-Dependent DNA Methylation Analysis in Liquid Biopsy Diagnostics for Cancer L Chamberlain, E Bram, O Savin, G Subramanian, E Bukin, P Barghouth, ... JOURNAL OF MOLECULAR DIAGNOSTICS 25 (11), S163-S163, 2023 | | 2023 |
| An Interlaced Pipeline for Translating NGS-Derived Methylation Biomarkers into Robust Multiplexed qPCR Assays for the Early Detection of Cancer M Dodge, P Barghouth, B Printy, T Gyuris, G Subramanian, G Mineo, ... JOURNAL OF MOLECULAR DIAGNOSTICS 24 (10), S153-S153, 2022 | | 2022 |
| ASD in Fragile X Syndrome: A FMR1-FMRP Molecular-Behavioral Study DB Budimirovic, RL Findling, K Nicholson, K Javanmardi, ... 66th Annual Meeting, 2019 | | 2019 |
Ron WeissProfessor of Biological Engineering, Massachusetts Institute of TechnologyVerified email at mit.edu
