John McKinney
John McKinney
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Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
JD McKinney, KH Zu Bentrup, EJ Muñoz-Elías, A Miczak, B Chen, ...
Nature 406 (6797), 735-738, 2000
Immune control of tuberculosis by IFN-γ-inducible LRG-47
JD MacMicking, GA Taylor, JD McKinney
Science 302 (5645), 654-659, 2003
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
EJ Muñoz-Elías, JD McKinney
Nature medicine 11 (6), 638-644, 2005
Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis
V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ...
Science 324 (5928), 801-804, 2009
M. tuberculosis persistence, latency, and drug tolerance
JE Gomez, JD McKinney
Tuberculosis 84 (1-2), 29-44, 2004
Dynamic persistence of antibiotic-stressed mycobacteria
Y Wakamoto, N Dhar, R Chait, K Schneider, F Signorino-Gelo, S Leibler, ...
Science 339 (6115), 91-95, 2013
Microbial phenotypic heterogeneity and antibiotic tolerance
N Dhar, JD McKinney
Current opinion in microbiology 10 (1), 30-38, 2007
Role of KatG catalase‐peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst
VH Ng, JS Cox, AO Sousa, JD MacMicking, JD McKinney
Molecular microbiology 52 (5), 1291-1302, 2004
Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence
EJ Muñoz‐Elías, AM Upton, J Cherian, JD McKinney
Molecular microbiology 60 (5), 1109-1122, 2006
Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis
V Sharma, S Sharma, KH Zu Bentrup, JD McKinney, DG Russell, ...
Nature structural biology 7 (8), 663-668, 2000
Carbon metabolism of intracellular bacteria
EJ Muñoz‐Elías, JD McKinney
Cellular microbiology 8 (1), 10-22, 2006
Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients
J Timm, FA Post, LG Bekker, GB Walther, HC Wainwright, R Manganelli, ...
Proceedings of the National Academy of Sciences 100 (24), 14321-14326, 2003
A problem of persistence: still more questions than answers?
NQ Balaban, K Gerdes, K Lewis, JD McKinney
Nature Reviews Microbiology 11 (8), 587-591, 2013
Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms
G Manina, N Dhar, JD McKinney
Cell host & microbe 17 (1), 32-46, 2015
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations
JE Griffin, AK Pandey, SA Gilmore, V Mizrahi, JD Mckinney, CR Bertozzi, ...
Chemistry & biology 19 (2), 218-227, 2012
Functional Characterization of a Vitamin B12-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during …
S Savvi, DF Warner, BD Kana, JD McKinney, V Mizrahi, SS Dawes
Journal of bacteriology 190 (11), 3886-3895, 2008
Replication Dynamics of Mycobacterium tuberculosis in Chronically Infected Mice
EJ Muñoz-Elías, J Timm, T Botha, WT Chan, JE Gomez, JD McKinney
Infection and immunity 73 (1), 546-551, 2005
Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
A Koul, L Vranckx, N Dhar, HWH Göhlmann, E Özdemir, JM Neefs, ...
Nature communications 5 (1), 3369, 2014
Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis
TA Gould, H Van De Langemheen, EJ Muñoz‐Elías, JD McKinney, ...
Molecular microbiology 61 (4), 940-947, 2006
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis
J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ...
Science translational medicine 4 (150), 150ra121-150ra121, 2012
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