SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... Science immunology 6 (58), eabg0833, 2021 | 151 | 2021 |
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells D Chauss, T Freiwald, R McGregor, B Yan, L Wang, E Nova-Lamperti, ... Nature immunology 23 (1), 62-74, 2022 | 146 | 2022 |
Aberrant type 1 immunity drives susceptibility to mucosal fungal infections TJ Break, V Oikonomou, N Dutzan, JV Desai, M Swidergall, T Freiwald, ... Science 371 (6526), eaay5731, 2021 | 98 | 2021 |
A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients F Hammer, U Malzahn, J Donhauser, C Betz, MP Schneider, C Grupp, ... Kidney international 95 (4), 983-991, 2019 | 84 | 2019 |
Diapedesis-induced integrin signaling via LFA-1 facilitates tissue immunity by inducing intrinsic complement C3 expression in immune cells M Kolev, EE West, N Kunz, D Chauss, EA Moseman, J Rahman, ... Immunity 52 (3), 513-527. e8, 2020 | 72 | 2020 |
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation N Niyonzima, J Rahman, N Kunz, EE West, T Freiwald, JV Desai, ... Science immunology 6 (66), eabf2489, 2021 | 59 | 2021 |
Native T1 and T2 provide distinctive signatures in hypertrophic cardiac conditions–Comparison of uremic, hypertensive and hypertrophic cardiomyopathy L Arcari, R Hinojar, J Engel, T Freiwald, S Platschek, H Zainal, H Zhou, ... International journal of cardiology 306, 102-108, 2020 | 57 | 2020 |
Extracorporeal virus elimination for the treatment of severe Ebola virus disease-first experience with lectin affinity plasmapheresis S Büttner, B Koch, O Dolnik, M Eickmann, T Freiwald, S Rudolf, J Engel, ... Blood purification 38 (3-4), 286-291, 2015 | 50 | 2015 |
Pattern recognition as a concept for multiple-choice questions in a national licensing exam T Freiwald, M Salimi, E Khaljani, S Harendza BMC medical education 14, 1-6, 2014 | 41 | 2014 |
SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyperactivation B Yan, T Freiwald, D Chauss, L Wang, E West, J Bibby, M Olson, ... Research Square, 2020 | 32 | 2020 |
Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance L Arcari, J Engel, T Freiwald, H Zhou, H Zainal, M Gawor, S Buettner, ... Journal of cardiovascular magnetic resonance 23 (1), 71, 2021 | 26 | 2021 |
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19 R McGregor, D Chauss, T Freiwald, B Yan, L Wang, E Nova-Lamperti, ... BioRxiv, 2020.07. 18.210161, 2020 | 26 | 2020 |
Systematic single-cell pathway analysis to characterize early T cell activation JA Bibby, D Agarwal, T Freiwald, N Kunz, NS Merle, EE West, P Singh, ... Cell reports 41 (8), 2022 | 25 | 2022 |
Aortic stiffness is independently associated with interstitial myocardial fibrosis by native T1 and accelerated in the presence of chronic kidney disease M Chen, L Arcari, J Engel, T Freiwald, S Platschek, H Zhou, H Zainal, ... IJC Heart & Vasculature 24, 100389, 2019 | 23 | 2019 |
C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection JV Desai, D Kumar, T Freiwald, D Chauss, MD Johnson, MS Abers, ... Cell 186 (13), 2802-2822. e22, 2023 | 20 | 2023 |
CD4+ T cell lymphopenia predicts mortality from Pneumocystis pneumonia in kidney transplant patients T Freiwald, S Büttner, NT Cheru, D Avaniadi, SS Martin, C Stephan, ... Clinical transplantation 34 (9), e13877, 2020 | 16 | 2020 |
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol. 2021 B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli | 15 | |
Renal diseases and the role of complement: linking complement to immune effector pathways and therapeutics T Freiwald, B Afzali Advances in immunology 152, 1-81, 2021 | 11 | 2021 |
Genomics and Computational Biology Core TJ Break, V Oikonomou, N Dutzan, JV Desai, M Swidergall, T Freiwald, ... Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD …, 2021 | 9 | 2021 |
The effect of spironolactone on diastolic function in haemodialysis patients T Hauser, V Dornberger, U Malzahn, SJ Grebe, D Liu, S Störk, M Nauck, ... The International Journal of Cardiovascular Imaging 37, 1927-1936, 2021 | 8 | 2021 |