Takip et
Simon Friedensohn
Simon Friedensohn
PhD Student at ETH Zürich
bsse.ethz.ch üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning
DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, SM Meng, ...
Nature Biomedical Engineering 5 (6), 600-612, 2021
1772021
Advanced methodologies in high-throughput sequencing of immune repertoires
S Friedensohn, TA Khan, ST Reddy
Trends in biotechnology 35 (3), 203-214, 2017
1342017
Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting
TA Khan, S Friedensohn, AR Gorter de Vries, J Straszewski, ...
Science advances 2 (3), e1501371, 2016
1312016
Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice
V Greiff, U Menzel, U Haessler, SC Cook, S Friedensohn, TA Khan, ...
BMC immunology 15, 1-14, 2014
672014
Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing
U Menzel, V Greiff, TA Khan, U Haessler, I Hellmann, S Friedensohn, ...
PloS one 9 (5), e96727, 2014
662014
Deep learning enables therapeutic antibody optimization in mammalian cells by deciphering high-dimensional protein sequence space
DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, S Meng, ...
BioRxiv, 617860, 2019
512019
Convergent selection in antibody repertoires is revealed by deep learning
S Friedensohn, D Neumeier, TA Khan, L Csepregi, C Parola, ...
BioRxiv, 2020.02. 25.965673, 2020
412020
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
F Sesterhenn, M Galloux, SS Vollers, L Csepregi, C Yang, D Descamps, ...
PLoS biology 17 (2), e3000164, 2019
352019
Synthetic standards combined with error and bias correction improve the accuracy and quantitative resolution of antibody repertoire sequencing in human naïve and memory B cells
S Friedensohn, JM Lindner, V Cornacchione, M Iazeolla, E Miho, A Zingg, ...
Frontiers in Immunology 9, 1401, 2018
332018
Antibody discovery and engineering by enhanced CRISPR-Cas9 integration of variable gene cassette libraries in mammalian cells
C Parola, D Neumeier, S Friedensohn, L Csepregi, M Di Tacchio, ...
MAbs 11 (8), 1367-1380, 2019
272019
SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display
RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ...
Cell reports 38 (3), 2022
142022
Cis-regulatory variation: significance in biomedicine and evolution
S Friedensohn, R Sawarkar
Cell and tissue research 356, 495-505, 2014
82014
Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2
RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ...
BioRxiv, 2021.02. 12.430940, 2021
72021
The physiological landscape and specificity of antibody repertoires
L Csepregi, KB Hoehn, D Neumeier, JM Taft, S Friedensohn, CR Weber, ...
bioRxiv, 2021.09. 15.460420, 2021
52021
Systems and methods to classify antibodies
D Mason, S Friedensohn, C Weber, S Reddy
US Patent App. 17/439,374, 2022
32022
Identification of convergent antibody specificity sequence patterns
S Friedensohn, S Reddy
US Patent App. 17/442,465, 2022
2022
Mining the sequence space of antibody repertoires to predict and design antigen-specific antibodies
S Friedensohn
ETH Zurich, 2020
2020
High-throughput sequencing error and bias correction increases the quantitative resolution of human naïve and memory B-cell receptor repertoires
JM Lindner, S Friedensohn, V Cornacchione, M Iazeolla, E Miho, A Zingg, ...
BioRxiv Preprint Server, 2018
2018
Correlations of antibody response phenotype to genotype revealed by molecular amplification fingerprinting
ST Reddy, TA Khan, S Friedensohn, AR Gorter de Vries
2016
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Makaleler 1–19