| Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling E Kickstein, S Krauss, P Thornhill, D Rutschow, R Zeller, J Sharkey, ... Proceedings of the National Academy of Sciences 107 (50), 21830-21835, 2010 | 471 | 2010 |
| Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-β peptide exposure: involvement of Src family protein kinases R Williamson, T Scales, BR Clark, G Gibb, CH Reynolds, S Kellie, IN Bird, ... Journal of Neuroscience 22 (1), 10-20, 2002 | 288 | 2002 |
| Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ... Molecular psychiatry 19 (1), 88-98, 2014 | 256 | 2014 |
| Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ... Journal of Neuroscience 25 (28), 6584-6593, 2005 | 229 | 2005 |
| Membrane‐bound β‐amyloid oligomers are recruited into lipid rafts by a fyn‐dependent mechanism R Williamson, A Usardi, DP Hanger, BH Anderton The FASEB Journal 22 (5), 1552-1559, 2008 | 152 | 2008 |
| Evidence that glycogen synthase kinase‐3 isoforms have distinct substrate preference in the brain MPM Soutar, WY Kim, R Williamson, M Peggie, CJ Hastie, H McLauchlan, ... Journal of neurochemistry 115 (4), 974-983, 2010 | 146 | 2010 |
| Insulin resistance in the brain: an old-age or new-age problem? R Williamson, A McNeilly, C Sutherland Biochemical pharmacology 84 (6), 737-745, 2012 | 120 | 2012 |
| High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task AD McNeilly, R Williamson, C Sutherland, DJK Balfour, CA Stewart Behavioural brain research 217 (1), 134-141, 2011 | 111 | 2011 |
| Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau A Usardi, AM Pooler, A Seereeram, CH Reynolds, P Derkinderen, ... The FEBS journal 278 (16), 2927-2937, 2011 | 98 | 2011 |
| A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin AD McNeilly, R Williamson, DJK Balfour, CA Stewart, C Sutherland Diabetologia 55, 3061-3070, 2012 | 96 | 2012 |
| The microtubule-associated protein tau is also phosphorylated on tyrosine T Lebouvier, TME Scales, R Williamson, W Noble, C Duyckaerts, ... Journal of Alzheimer's Disease 18 (1), 1-9, 2009 | 92 | 2009 |
| The antidepressant clomipramine regulates cortisol intracellular concentrations and glucocorticoid receptor expression in fibroblasts and rat primary neurones CM Pariante, A Hye, R Williamson, A Makoff, S Lovestone, RW Kerwin Neuropsychopharmacology 28 (9), 1553-1561, 2003 | 92 | 2003 |
| CRMP2 hyperphosphorylation is characteristic of Alzheimer's disease and not a feature common to other neurodegenerative diseases R Williamson, L Van Aalten, D Mann, B Platt, F Plattner, L Bedford, ... Journal of Alzheimer's Disease 27 (3), 615-625, 2011 | 72 | 2011 |
| A mutant O-GlcNAcase enriches Drosophila developmental regulators N Selvan, R Williamson, D Mariappa, DG Campbell, R Gourlay, ... Nature chemical biology 13 (8), 882-887, 2017 | 61 | 2017 |
| Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn TME Scales, P Derkinderen, KY Leung, HL Byers, MA Ward, C Price, ... Molecular neurodegeneration 6, 1-11, 2011 | 56 | 2011 |
| Lobeline and structurally simplified analogs exhibit differential agonist activity and sensitivity to antagonist blockade when compared to nicotine AV Terry Jr, R Williamson, M Gattu, JW Beach, CR McCurdy, JA Sparks, ... Neuropharmacology 37 (1), 93-102, 1998 | 56 | 1998 |
| Neuronal membranes are key to the pathogenesis of Alzheimer's disease: the role of both raft and non-raft membrane domains R Williamson, C Sutherland Current Alzheimer Research 8 (2), 213-221, 2011 | 48 | 2011 |
| Isolation of detergent resistant microdomains from cultured neurons: detergent dependent alterations in protein composition R Williamson, AJ Thompson, M Abu, A Hye, A Usardi, S Lynham, ... BMC neuroscience 11, 1-12, 2010 | 36 | 2010 |
| Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes PG Weightman Potter, JM Vlachaki Walker, JL Robb, JK Chilton, ... Diabetologia 62, 187-198, 2019 | 33 | 2019 |
| Endoplasmic reticulum stress signalling induces casein kinase 1-dependent formation of cytosolic TDP-43 inclusions in motor neuron-like cells DA Hicks, LL Cross, R Williamson, M Rattray Neurochemical research 45, 1354-1364, 2020 | 29 | 2020 |
