| High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents J Ma, L Guo, SJ Fiene, BD Anson, JA Thomson, TJ Kamp, KL Kolaja, ... American Journal of Physiology-Heart and Circulatory Physiology 301 (5 …, 2011 | 864 | 2011 |
| The role of oxidative stress in chemical carcinogenesis. JE Klaunig, Y Xu, JS Isenberg, S Bachowski, KL Kolaja, J Jiang, ... Environmental health perspectives 106 (suppl 1), 289-295, 1998 | 725 | 1998 |
| Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes T Force, KL Kolaja Nature reviews Drug discovery 10 (2), 111-126, 2011 | 395 | 2011 |
| Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action B Ganter, S Tugendreich, CI Pearson, E Ayanoglu, S Baumhueter, ... Journal of biotechnology 119 (3), 219-244, 2005 | 325 | 2005 |
| Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell–derived cardiomyocytes L Guo, RMC Abrams, JE Babiarz, JD Cohen, S Kameoka, MJ Sanders, ... Toxicological Sciences 123 (1), 281-289, 2011 | 311 | 2011 |
| Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells FM Drawnel, S Boccardo, M Prummer, F Delobel, A Graff, M Weber, ... Cell reports 9 (3), 810-820, 2014 | 251 | 2014 |
| Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro W Hu, C Sorrentino, MS Denison, K Kolaja, MR Fielden Molecular pharmacology 71 (6), 1475-1486, 2007 | 244 | 2007 |
| Opportunities for use of human iPS cells in predictive toxicology BD Anson, KL Kolaja, TJ Kamp Clinical Pharmacology & Therapeutics 89 (5), 754-758, 2011 | 168 | 2011 |
| 4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization DP Hartley, KL Kolaja, J Reichard, DR Petersen Toxicology and applied pharmacology 161 (1), 23-33, 1999 | 147 | 1999 |
| Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model L Guo, L Coyle, RMC Abrams, R Kemper, ET Chiao, KL Kolaja toxicological sciences 136 (2), 581-594, 2013 | 132 | 2013 |
| A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity MR Fielden, BP Eynon, G Natsoulis, K Jarnagin, D Banas, KL Kolaja Toxicologic pathology 33 (6), 675-683, 2005 | 129 | 2005 |
| Role of oxidative stress in the mechanism of dieldrin's hepatotoxicity S Bachowski, KL Kolaja, Y Xu, CA Ketcham, DE Stevenson, EF Walborg, ... Annals of Clinical & Laboratory Science 27 (3), 196-209, 1997 | 112 | 1997 |
| Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line MF Peters, SD Lamore, L Guo, CW Scott, KL Kolaja Cardiovascular Toxicology 15, 127-139, 2015 | 102 | 2015 |
| Determination of the human cardiomyocyte mRNA and miRNA differentiation network by fine-scale profiling JE Babiarz, M Ravon, S Sridhar, P Ravindran, B Swanson, H Bitter, ... Stem cells and development 21 (11), 1956-1965, 2012 | 101 | 2012 |
| Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations JD Cohen, JE Babiarz, RM Abrams, L Guo, S Kameoka, E Chiao, ... Toxicology and applied pharmacology 257 (1), 74-83, 2011 | 92 | 2011 |
| Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling JA Kramer, SW Curtiss, KL Kolaja, CL Alden, EAG Blomme, WC Curtiss, ... Chemical research in toxicology 17 (4), 463-470, 2004 | 84 | 2004 |
| Cancer genetics and the cardiotoxicity of the therapeutics H Lal, KL Kolaja, T Force Journal of the American College of Cardiology 61 (3), 267-274, 2013 | 81 | 2013 |
| The role of early in vivo toxicity testing in drug discovery toxicology MR Fielden, KL Kolaja Expert opinion on drug safety 7 (2), 107-110, 2008 | 78 | 2008 |
| A high-throughput screen for teratogens using human pluripotent stem cells S Kameoka, J Babiarz, K Kolaja, E Chiao toxicological sciences 137 (1), 76-90, 2014 | 75 | 2014 |
| The electrophysiological effects of cardiac glycosides in human iPSC-derived cardiomyocytes and in guinea pig isolated hearts L Guo, JY Qian, R Abrams, HM Tang, T Weiser, MJ Sanders, KL Kolaja Cellular Physiology and Biochemistry 27 (5), 453-462, 2011 | 75 | 2011 |
