Hepatitis C virus E2 envelope glycoprotein core structure L Kong, E Giang, T Nieusma, RU Kadam, KE Cogburn, Y Hua, X Dai, ... Science 342 (6162), 1090-1094, 2013 | 335 | 2013 |
Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol RU Kadam, IA Wilson Proceedings of the National Academy of Sciences 114 (2), 206-214, 2017 | 231 | 2017 |
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB EMV Johansson, SA Crusz, E Kolomiets, L Buts, RU Kadam, M Cacciarini, ... Chemistry & biology 15 (12), 1249-1257, 2008 | 217 | 2008 |
A glycopeptide dendrimer inhibitor of the galactose‐specific lectin LecA and of Pseudomonas aeruginosa biofilms RU Kadam, M Bergmann, M Hurley, D Garg, M Cacciarini, MA Swiderska, ... Angewandte Chemie International Edition 50 (45), 10631-10635, 2011 | 141 | 2011 |
Recent trends in drug-likeness prediction: a comprehensive review of in silico methods RU Kadam, N Roy Indian Journal of Pharmaceutical Sciences 69 (5), 609, 2007 | 87 | 2007 |
Potent peptidic fusion inhibitors of influenza virus RU Kadam, J Juraszek, B Brandenburg, C Buyck, WBG Schepens, ... Science 358 (6362), 496-502, 2017 | 85 | 2017 |
Glycopeptide Dendrimers with High Affinity for the Fucose‐Binding Lectin LecB from Pseudomonas aeruginosa E Kolomiets, MA Swiderska, RU Kadam, EMV Johansson, KE Jaeger, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 562-569, 2009 | 84 | 2009 |
CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA RU Kadam, D Garg, J Schwartz, R Visini, M Sattler, A Stocker, T Darbre, ... ACS chemical biology 8 (9), 1925-1930, 2013 | 81 | 2013 |
A small-molecule fusion inhibitor of influenza virus is orally active in mice MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ... Science 363 (6431), 2019 | 53 | 2019 |
Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids E Johansson, RU Kadam MedChemComm 2 (5), 418-420, 2011 | 51 | 2011 |
Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen L Kong, DE Lee, RU Kadam, T Liu, E Giang, T Nieusma, F Garces, ... Proceedings of the National Academy of Sciences 113 (45), 12768-12773, 2016 | 49 | 2016 |
Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini M Stach, N Maillard, RU Kadam MedChemComm 3 (1), 86-89, 2012 | 48 | 2012 |
Structure‐Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA RU Kadam, M Bergmann, D Garg, G Gabrieli, A Stocker, T Darbre, ... Chemistry–A European Journal 19 (50), 17054-17063, 2013 | 37 | 2013 |
Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314–324 in complex with antibody IGH526 L Kong, RU Kadam, E Giang, TB Ruwona, T Nieusma, JC Culhane, ... Journal of molecular biology 427 (16), 2617-2628, 2015 | 32 | 2015 |
Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility NC Wu, H Lv, AJ Thompson, DC Wu, WWS Ng, RU Kadam, CW Lin, ... Cell host & microbe 25 (6), 836-844. e5, 2019 | 30 | 2019 |
Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin ZVF Wright, NC Wu, RU Kadam, IA Wilson, DW Wolan Bioorganic & medicinal chemistry letters 27 (16), 3744-3748, 2017 | 30 | 2017 |
Cluster analysis and two-dimensional quantitative structure–activity relationship (2D-QSAR) of Pseudomonas aeruginosa deacetylase LpxC inhibitors RU Kadam, N Roy Bioorganic & medicinal chemistry letters 16 (19), 5136-5143, 2006 | 25 | 2006 |
Structure and Binding of Peptide‐Dendrimer Ligands to Vitamin B12 NA Uhlich, A Natalello, RU Kadam, SM Doglia, JL Reymond, T Darbre ChemBioChem 11 (3), 358-365, 2010 | 22 | 2010 |
Structure Function Analysis of Leishmania Sirtuin: An Ensemble of In Silico and Biochemical Studies RU Kadam, J Tavares, A Cordeiro, A Ouaissi, N Roy Chemical biology & drug design 71 (5), 501-506, 2008 | 20 | 2008 |
Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling D Das, M Hervé, MA Elsliger, RU Kadam, JC Grant, HJ Chiu, MW Knuth, ... Journal of bacteriology 195 (24), 5555-5566, 2013 | 17 | 2013 |