| An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation D Iliopoulos, HA Hirsch, K Struhl Cell 139 (4), 693-706, 2009 | 1643 | 2009 |
| New genetic loci link adipose and insulin biology to body fat distribution D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ... Nature 518 (7538), 187-196, 2015 | 1594 | 2015 |
| Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission HA Hirsch, D Iliopoulos, PN Tsichlis, K Struhl Cancer research 69 (19), 7507-7511, 2009 | 1350 | 2009 |
| E2F1-regulated microRNAs impair TGFβ-dependent cell-cycle arrest and apoptosis in gastric cancer F Petrocca, R Visone, MR Onelli, MH Shah, MS Nicoloso, I de Martino, ... Cancer cell 13 (3), 272-286, 2008 | 1160 | 2008 |
| STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer D Iliopoulos, SA Jaeger, HA Hirsch, ML Bulyk, K Struhl Molecular cell 39 (4), 493-506, 2010 | 995 | 2010 |
| XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway X Chen, D Iliopoulos, Q Zhang, Q Tang, MB Greenblatt, M Hatziapostolou, ... Nature 508 (7494), 103-107, 2014 | 829 | 2014 |
| Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion D Iliopoulos, HA Hirsch, G Wang, K Struhl Proceedings of the National Academy of Sciences 108 (4), 1397-1402, 2011 | 746 | 2011 |
| Environmental triggers in IBD: a review of progress and evidence AN Ananthakrishnan, CN Bernstein, D Iliopoulos, A Macpherson, ... Nature reviews Gastroenterology & hepatology 15 (1), 39-49, 2018 | 721 | 2018 |
| Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms E Piskounova, C Polytarchou, JE Thornton, RJ LaPierre, C Pothoulakis, ... Cell 147 (5), 1066-1079, 2011 | 708 | 2011 |
| The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs A Androulidaki, D Iliopoulos, A Arranz, C Doxaki, S Schworer, ... Immunity 31 (2), 220-231, 2009 | 675 | 2009 |
| Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks D Iliopoulos, KN Malizos, P Oikonomou, A Tsezou PloS one 3 (11), e3740, 2008 | 590 | 2008 |
| An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis M Hatziapostolou, C Polytarchou, E Aggelidou, A Drakaki, GA Poultsides, ... Cell 147 (6), 1233-1247, 2011 | 554 | 2011 |
| Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types D Iliopoulos, HA Hirsch, K Struhl Cancer research 71 (9), 3196-3201, 2011 | 543 | 2011 |
| Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth HA Hirsch, D Iliopoulos, K Struhl Proceedings of the National Academy of Sciences 110 (3), 972-977, 2013 | 485 | 2013 |
| Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling G He, D Dhar, H Nakagawa, J Font-Burgada, H Ogata, Y Jiang, ... Cell 155 (2), 384-396, 2013 | 480 | 2013 |
| Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells D Iliopoulos, M Lindahl-Allen, C Polytarchou, HA Hirsch, PN Tsichlis, ... Molecular cell 39 (5), 761-772, 2010 | 464 | 2010 |
| NLR family member NLRC5 is a transcriptional regulator of MHC class I genes TB Meissner, A Li, A Biswas, KH Lee, YJ Liu, E Bayir, D Iliopoulos, ... Proceedings of the National Academy of Sciences 107 (31), 13794-13799, 2010 | 448 | 2010 |
| MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism [S] D Iliopoulos, K Drosatos, Y Hiyama, IJ Goldberg, VI Zannis Journal of lipid research 51 (6), 1513-1523, 2010 | 385 | 2010 |
| A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases HA Hirsch, D Iliopoulos, A Joshi, Y Zhang, SA Jaeger, M Bulyk, ... Cancer cell 17 (4), 348-361, 2010 | 385 | 2010 |
| The IBD interactome: an integrated view of aetiology, pathogenesis and therapy HSP De Souza, C Fiocchi, D Iliopoulos Nature Reviews Gastroenterology & Hepatology 14 (12), 739-749, 2017 | 371 | 2017 |
