| Quantitative transporter proteomics by liquid chromatography with tandem mass spectrometry: addressing methodologic issues of plasma membrane isolation and expression-activity … V Kumar, B Prasad, G Patilea, A Gupta, L Salphati, R Evers, CECA Hop, ... Drug Metabolism and Disposition 43 (2), 284-288, 2015 | 50 | 2015 |
| Positron Emission Tomography Imaging of [11C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of … S Billington, S Shoner, S Lee, K Clark‐Snustad, M Pennington, D Lewis, ... Clinical Pharmacology & Therapeutics 106 (5), 1056-1066, 2019 | 44 | 2019 |
| A comparison of total and plasma membrane abundance of transporters in suspended, plated, sandwich-cultured human hepatocytes versus human liver tissue using quantitative … V Kumar, L Salphati, CECA Hop, G Xiao, Y Lai, A Mathias, X Chu, ... Drug Metabolism and Disposition 47 (4), 350-357, 2019 | 44 | 2019 |
| The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance V Kumar, J Yin, S Billington, B Prasad, CDA Brown, J Wang, JD Unadkat Drug Metabolism and Disposition 46 (10), 1441-1445, 2018 | 41 | 2018 |
| Targeted LC-MS/MS proteomics-based strategy to characterize in vitro models used in drug metabolism and transport studies M Xu, N Saxena, M Vrana, H Zhang, V Kumar, S Billington, C Khojasteh, ... Analytical chemistry 90 (20), 11873-11882, 2018 | 32 | 2018 |
| Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach V Kumar, M Yin, K Ishida, L Salphati, CECA Hop, C Rowbottom, G Xiao, ... Drug Metabolism and Disposition, 159-168, 2021 | 24 | 2021 |
| Optimization and application of a biotinylation method for quantification of plasma membrane expression of transporters in cells V Kumar, TB Nguyen, B Tóth, V Juhasz, JD Unadkat The AAPS journal 19, 1377-1386, 2017 | 23 | 2017 |
| Practical and economical implementation of online H/D exchange in LC-MS RP Shah, A Garg, SP Putlur, S Wagh, V Kumar, V Rao, S Singh, ... Analytical chemistry 85 (22), 10904-10912, 2013 | 18 | 2013 |
| Successful Prediction of Positron Emission Tomography–Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics–Informed Relative Expression Factor … M Sachar, V Kumar, LC Gormsen, OL Munk, JD Unadkat Drug Metabolism and Disposition 48 (11), 1210-1216, 2020 | 17 | 2020 |
| Mechanistic modeling of central nervous system pharmacokinetics and target engagement of HER2 tyrosine kinase inhibitors to inform treatment of breast cancer brain metastases J Li, J Jiang, X Bao, V Kumar, SC Alley, S Peterson, AJ Lee Clinical Cancer Research 28 (15), 3329-3341, 2022 | 9 | 2022 |
| Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl H Sun, KA Cardinal, L Wienkers, A Chin, V Kumar, C Neace, ... Cancer chemotherapy and pharmacology 89 (6), 737-750, 2022 | 8 | 2022 |
| Pitfalls in predicting hepatobiliary drug transport using human sandwich-cultured hepatocytes V Kumar, CY Li, K Ishida, E Kis, Z Gáborik, JD Unadkat The AAPS Journal 22, 1-11, 2020 | 7 | 2020 |
| 295P Physiologically based pharmacokinetic (PBPK) modeling of the central nervous system (CNS) pharmacokinetics of tucatinib in patients with breast cancer brain metastasis AJ Lee, J Jiang, V Kumar, SC Alley, S Peterson, J Li Annals of Oncology 31, S360, 2020 | 6 | 2020 |
| Prediction of hepatobiliary clearances and hepatic concentrations of transported drugs in humans using rosuvastatin as a model drug F Storelli, CY Li, M Sachar, V Kumar, S Heyward, Z Sáfár, E Kis, ... Clinical Pharmacology & Therapeutics 112 (3), 593-604, 2022 | 4 | 2022 |
| SGN-B6A: A New Vedotin Antibody–Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications RP Lyon, M Jonas, C Frantz, ES Trueblood, R Yumul, L Westendorf, ... Molecular Cancer Therapeutics 22 (12), 1444-1453, 2023 | 2 | 2023 |
| Activity of SGN-B6A in patient-derived xenograft models of non-small cell lung cancer RP Lyon, JJ Gosink, JL Stillwell, CJ Hale, S Allred, KM Hensley, V Kumar, ... American Association of Cancer Research, Virtual Annual Meeting; April 10, 15, 2021 | 2 | 2021 |
| Tucatinib does not alter oxaliplatin PK or associated renal function: An OCT2 and MATE transport inhibition study AR Topletz-Erickson, A Lee, V Kumar, M Ubowski, JAG Mayor, ... Cancer Research 83 (7_Supplement), 5060-5060, 2023 | | 2023 |
| P129-In-vivo transporter-mediated hepatic clearance of rosuvastatin in humans could be better predicted using transporter-expressing cells than hepatocytes V Kumar, K Ishida, L Salphati, CECA Hop, C Rowbottom, G Xiao, Y Lai, ... Drug Metabolism and Pharmacokinetics 35 (1), S61-S62, 2020 | | 2020 |
| 22nd North American ISSX Meeting Speaker Abstracts M Cancilla 22ND NORTH AMERICAN ISSX MEETING 1 (S1), 21, 2018 | | 2018 |
| Abstract A67: Syntheses and antitumor activities on NCI-60 human tumor cell line protocol of novel N-hydroxyethyl-4-aza-didehyropodophyllotoxin derivatives with halo … A Kumar, V Kumar, AE Alegria, MV Sanjay Cancer Prevention Research 5 (11_Supplement), A67-A67, 2012 | | 2012 |
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