Takip et
Rob van der Kant
Rob van der Kant
Postdoctoral Researcher KULeuven
kuleuven.vib.be üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Prediction and reduction of the aggregation of monoclonal antibodies
R van der Kant, AR Karow-Zwick, J Van Durme, M Blech, R Gallardo, ...
Journal of molecular biology 429 (8), 1244-1261, 2017
1452017
GPCRDB: an information system for G protein-coupled receptors
V Isberg, B Vroling, R van der Kant, K Li, G Vriend, D Gloriam
Nucleic acids research 42 (D1), D422-D425, 2014
1382014
Hsp90 mediates membrane deformation and exosome release
E Lauwers, YC Wang, R Gallardo, R Van der Kant, E Michiels, J Swerts, ...
Molecular cell 71 (5), 689-702. e9, 2018
1372018
Solubis: a webserver to reduce protein aggregation through mutation
J Van Durme, G De Baets, R Van Der Kant, M Ramakers, A Ganesan, ...
Protein Engineering, Design and Selection 29 (8), 285-289, 2016
672016
Post-translational control of the temporal dynamics of transcription factor activity regulates neurogenesis
XJ Quan, L Yuan, L Tiberi, A Claeys, N De Geest, J Yan, R Van Der Kant, ...
Cell 164 (3), 460-475, 2016
642016
Structural hot spots for the solubility of globular proteins
A Ganesan, A Siekierska, J Beerten, M Brams, J Van Durme, G De Baets, ...
Nature communications 7 (1), 10816, 2016
622016
Alpha-bulges in G protein-coupled receptors
R Van der Kant, G Vriend
International journal of molecular sciences 15 (5), 7841-7864, 2014
452014
Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia
E Van Nieuwenhove, JS Barber, J Neumann, E Smeets, M Willemsen, ...
Journal of Allergy and Clinical Immunology 146 (5), 1180-1193, 2020
392020
Thermodynamic and evolutionary coupling between the native and amyloid state of globular proteins
T Langenberg, R Gallardo, R van der Kant, N Louros, E Michiels, ...
Cell reports 31 (2), 2020
372020
Reverse engineering synthetic antiviral amyloids
E Michiels, K Roose, R Gallardo, L Khodaparast, L Khodaparast, ...
Nature communications 11 (1), 2832, 2020
352020
Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues
B Houben, E Michiels, M Ramakers, K Konstantoulea, N Louros, ...
The EMBO journal 39 (11), e102864, 2020
322020
Thermodynamic analysis of amyloid fibril structures reveals a common framework for stability in amyloid polymorphs
R van der Kant, N Louros, J Schymkowitz, F Rousseau
Structure 30 (8), 1178-1189. e3, 2022
23*2022
Solubis: optimize your protein
G De Baets, J Van Durme, R van der Kant, J Schymkowitz, F Rousseau
Bioinformatics 31 (15), 2580-2582, 2015
222015
Adaption of human antibody λ and κ light chain architectures to CDR repertoires
R van der Kant, J Bauer, AR Karow-Zwick, S Kube, P Garidel, M Blech, ...
Protein Engineering, Design and Selection 32 (3), 109-127, 2019
152019
The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis
N Guthertz, R Van Der Kant, RM Martinez, Y Xu, CH Trinh, BI Iorga, ...
Proceedings of the National Academy of Sciences 119 (22), e2200468119, 2022
102022
StAmP-DB: a platform for structures of polymorphic amyloid fibril cores
N Louros, R Van Der Kant, J Schymkowitz, F Rousseau
Bioinformatics 38 (9), 2636-2638, 2022
102022
SolubiS: Optimizing protein solubility by minimal point mutations
R van der Kant, J van Durme, F Rousseau, J Schymkowitz
Protein Misfolding Diseases: Methods and Protocols, 317-333, 2019
92019
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V
F Claes, S Rudyak, AS Laird, N Louros, J Beerten, M Debulpaep, ...
Protein Engineering, Design and Selection 32 (10), 443-457, 2019
62019
Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein
K Janssen, F Claes, D Van de Velde, VL Wehbi, B Houben, Y Lampi, ...
Proceedings of the National Academy of Sciences 120 (9), e2214921120, 2023
32023
De novo design of high-affinity single-domain antibodies
R Van Der Kant, Z Zhang, I Marković, D Vizarraga, T Garcia, K Maragkou, ...
bioRxiv, 2024.04. 22.589762, 2024
2024
Sistem, işlemi şu anda gerçekleştiremiyor. Daha sonra yeniden deneyin.
Makaleler 1–20