| Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1α I Mylonis, G Chachami, M Samiotaki, G Panayotou, E Paraskeva, ... Journal of Biological Chemistry 281 (44), 33095-33106, 2006 | 363 | 2006 |
| Ubiquitin‐specific protease‐like 1 (USPL1) is a SUMO isopeptidase with essential, non‐catalytic functions S Schulz, G Chachami, L Kozaczkiewicz, U Winter, N Stankovic‐Valentin, ... EMBO reports 13 (10), 930-938, 2012 | 201 | 2012 |
| Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1α by MAPK I Mylonis, G Chachami, E Paraskeva, G Simos Journal of biological chemistry 283 (41), 27620-27627, 2008 | 142 | 2008 |
| Casein kinase 1 regulates human hypoxia-inducible factor HIF-1 A Kalousi, I Mylonis, AS Politou, G Chachami, E Paraskeva, G Simos Journal of cell science 123 (17), 2976-2986, 2010 | 121 | 2010 |
| Transport of hypoxia-inducible factor HIF-1α into the nucleus involves importins 4 and 7 G Chachami, E Paraskeva, JM Mingot, GG Braliou, D Görlich, G Simos Biochemical and biophysical research communications 390 (2), 235-240, 2009 | 119 | 2009 |
| Cobalt induces hypoxia-inducible factor-1α expression in airway smooth muscle cells by a reactive oxygen species–and PI3K-dependent mechanism G Chachami, G Simos, A Hatziefthimiou, S Bonanou, PA Molyvdas, ... American journal of respiratory cell and molecular biology 31 (5), 544-551, 2004 | 117 | 2004 |
| Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect S Darekar, K Georgiou, M Yurchenko, SP Yenamandra, G Chachami, ... Public Library of Science 7 (7), e42072, 2012 | 94 | 2012 |
| 2-Oxoglutarate-dependent oxygenases control hepcidin gene expression GG Braliou, MVV Falzacappa, G Chachami, G Casanovas, ... Journal of hepatology 48 (5), 801-810, 2008 | 92 | 2008 |
| MgcRacGAP interacts with HIF-1α and regulates its transcriptional activity A Lyberopoulou, E Venieris, I Mylonis, G Chachami, I Pappas, G Simos, ... Cellular Physiology and Biochemistry 20 (6), 995-1006, 2007 | 67 | 2007 |
| A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II S Hutten, G Chachami, U Winter, F Melchior, AI Lamond Journal of cell science 127 (5), 1065-1078, 2014 | 58 | 2014 |
| The flavonoid quercetin induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation by depleting intracellular iron A Triantafyllou, P Liakos, A Tsakalof, G Chachami, E Paraskeva, ... Free radical research 41 (3), 342-356, 2007 | 56 | 2007 |
| The role of sumoylation in the response to hypoxia: an overview C Filippopoulou, G Simos, G Chachami Cells 9 (11), 2359, 2020 | 42 | 2020 |
| Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen*[S] G Chachami, N Stankovic-Valentin, A Karagiota, A Basagianni, ... Molecular & Cellular Proteomics 18 (6), 1197-1209, 2019 | 31 | 2019 |
| Low serum hepcidin in patients with autoimmune liver diseases A Lyberopoulou, G Chachami, NK Gatselis, E Kyratzopoulou, A Saitis, ... PloS one 10 (8), e0135486, 2015 | 31 | 2015 |
| Bacterially produced human HIF-1α is competent for heterodimerization and specific DNA-binding G Chachami, E Paraskeva, E Georgatsou, S Bonanou, G Simos Biochemical and biophysical research communications 331 (2), 464-470, 2005 | 29 | 2005 |
| Exposure of differentiated airway smooth muscle cells to serum stimulates both induction of hypoxia-inducible factor-1α and airway responsiveness to ACh G Chachami, A Hatziefthimiou, P Liakos, MG Ioannou, GK Koukoulis, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (4 …, 2007 | 22 | 2007 |
| Transcriptional response to hypoxia: the role of HIF-1-associated co-regulators A Yfantis, I Mylonis, G Chachami, M Nikolaidis, GD Amoutzias, ... Cells 12 (5), 798, 2023 | 20 | 2023 |
| Insulin causes a transient induction of proliferation via activation of the PI3-kinase pathway in airway smooth muscle cells M Papagianni, A Hatziefthimiou, G Chachami, K Gourgoulianis, ... Experimental and clinical endocrinology & diabetes 115 (02), 118-123, 2007 | 19 | 2007 |
| An association study between hypoxia inducible factor-1alpha (HIF-1α) polymorphisms and osteonecrosis G Chachami, A Kalousi, L Papatheodorou, A Lyberopoulou, V Nasikas, ... PLoS One 8 (11), e79647, 2013 | 17 | 2013 |
| Lipid metabolism in cancer: The role of acylglycerolphosphate acyltransferases (AGPATs) A Karagiota, G Chachami, E Paraskeva Cancers 14 (1), 228, 2022 | 15 | 2022 |
