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Antonella Caccamo
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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction
S Oddo, A Caccamo, JD Shepherd, MP Murphy, TE Golde, R Kayed, ...
Neuron 39 (3), 409-421, 2003
48022003
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer’s disease
S Oddo, A Caccamo, M Kitazawa, BP Tseng, FM LaFerla
Neurobiology of aging 24 (8), 1063-1070, 2003
12412003
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-β, and Tau: effects on cognitive impairments
A Caccamo, S Majumder, A Richardson, R Strong, S Oddo
Journal of Biological Chemistry 285 (17), 13107-13120, 2010
9712010
M1 receptors play a central role in modulating AD-like pathology in transgenic mice
A Caccamo, S Oddo, LM Billings, KN Green, H Martinez-Coria, A Fisher, ...
Neuron 49 (5), 671-682, 2006
5192006
Temporal profile of amyloid-β (Aβ) oligomerization in an in vivo model of Alzheimer disease: a link between Aβ and tau pathology
S Oddo, A Caccamo, L Tran, MP Lambert, CG Glabe, WL Klein, ...
Journal of Biological Chemistry 281 (3), 1599-1604, 2006
5192006
Reduction of soluble Aβ and tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles
S Oddo, V Vasilevko, A Caccamo, M Kitazawa, DH Cribbs, FM LaFerla
Journal of Biological Chemistry 281 (51), 39413-39423, 2006
4122006
Age-and region-dependent alterations in Aβ-degrading enzymes: implications for Aβ-induced disorders
A Caccamo, S Oddo, MC Sugarman, Y Akbari, FM LaFerla
Neurobiology of aging 26 (5), 645-654, 2005
4032005
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice
GE Stutzmann, I Smith, A Caccamo, S Oddo, FM LaFerla, I Parker
Journal of Neuroscience 26 (19), 5180-5189, 2006
3842006
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies
A Caccamo, A Magrì, DX Medina, EV Wisely, MF López‐Aranda, AJ Silva, ...
Aging cell 12 (3), 370-380, 2013
3822013
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice
LK Clinton, LM Billings, KN Green, A Caccamo, J Ngo, S Oddo, ...
Neurobiology of disease 28 (1), 76-82, 2007
3542007
Necroptosis activation in Alzheimer's disease
A Caccamo, C Branca, IS Piras, E Ferreira, MJ Huentelman, WS Liang, ...
Nature neuroscience 20 (9), 1236-1246, 2017
3502017
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered …
GE Stutzmann, A Caccamo, FM LaFerla, I Parker
Journal of Neuroscience 24 (2), 508-513, 2004
3302004
A dynamic relationship between intracellular and extracellular pools of Aβ
S Oddo, A Caccamo, IF Smith, KN Green, FM LaFerla
The American journal of pathology 168 (1), 184-194, 2006
3072006
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease
A Caccamo, MA Maldonado, AF Bokov, S Majumder, S Oddo
Proceedings of the National Academy of Sciences 107 (52), 22687-22692, 2010
2752010
Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease
S Oddo, A Caccamo, KN Green, K Liang, L Tran, Y Chen, FM Leslie, ...
Proceedings of the National Academy of Sciences 102 (8), 3046-3051, 2005
2592005
Methylene blue reduces Aβ levels and rescues early cognitive deficit by increasing proteasome activity
DX Medina, A Caccamo, S Oddo
Brain pathology 21 (2), 140-149, 2011
2492011
Lithium reduces tau phosphorylation but not Aβ or working memory deficits in a transgenic model with both plaques and tangles
A Caccamo, S Oddo, LX Tran, FM LaFerla
The American journal of pathology 170 (5), 1669-1675, 2007
2372007
Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice
R Belfiore, A Rodin, E Ferreira, R Velazquez, C Branca, A Caccamo, ...
Aging cell 18 (1), e12873, 2019
2342019
Lifelong rapamycin administration ameliorates age‐dependent cognitive deficits by reducing IL‐1β and enhancing NMDA signaling
S Majumder, A Caccamo, DX Medina, AD Benavides, MA Javors, E Kraig, ...
Aging cell 11 (2), 326-335, 2012
2272012
Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature
A Caccamo, V De Pinto, A Messina, C Branca, S Oddo
Journal of Neuroscience 34 (23), 7988-7998, 2014
1952014
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