| Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer A Carracedo, L Ma, J Teruya-Feldstein, F Rojo, L Salmena, A Alimonti, ... The Journal of clinical investigation 118 (9), 3065-3074, 2008 | 1666 | 2008 |
| Tenets of PTEN tumor suppression L Salmena, A Carracedo, PP Pandolfi Cell 133 (3), 403-414, 2008 | 1305 | 2008 |
| Cancer metabolism: fatty acid oxidation in the limelight A Carracedo, LC Cantley, PP Pandolfi Nature Reviews Cancer 13 (4), 227-232, 2013 | 1218 | 2013 |
| The PTEN–PI3K pathway: of feedbacks and cross-talks A Carracedo, PP Pandolfi Oncogene 27 (41), 5527-5541, 2008 | 1095 | 2008 |
| SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization LWS Finley, A Carracedo, J Lee, A Souza, A Egia, J Zhang, ... Cancer cell 19 (3), 416-428, 2011 | 891 | 2011 |
| Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells M Salazar, A Carracedo, ÍJ Salanueva, S Hernández-Tiedra, M Lorente, ... The Journal of clinical investigation 119 (5), 1359-1372, 2009 | 804 | 2009 |
| Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate BS Carver, J Tran, A Gopalan, Z Chen, S Shaikh, A Carracedo, A Alimonti, ... Nature genetics 41 (5), 619-624, 2009 | 777 | 2009 |
| A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance K Ito, A Carracedo, D Weiss, F Arai, U Ala, DE Avigan, ZT Schafer, ... Nature medicine 18 (9), 1350-1358, 2012 | 715 | 2012 |
| Subtle variations in Pten dose determine cancer susceptibility A Alimonti, A Carracedo, JG Clohessy, LC Trotman, C Nardella, A Egia, ... Nature genetics 42 (5), 454-458, 2010 | 679 | 2010 |
| The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network MS Song, L Salmena, A Carracedo, A Egia, F Lo-Coco, ... Nature 455 (7214), 813-817, 2008 | 615 | 2008 |
| High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia A Gutierrez, T Sanda, R Grebliunaite, A Carracedo, L Salmena, Y Ahn, ... Blood, The Journal of the American Society of Hematology 114 (3), 647-650, 2009 | 501 | 2009 |
| Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner MS Song, A Carracedo, L Salmena, SJ Song, A Egia, M Malumbres, ... Cell 144 (2), 187-199, 2011 | 446 | 2011 |
| Systemic elevation of PTEN induces a tumor-suppressive metabolic state I Garcia-Cao, MS Song, RM Hobbs, G Laurent, C Giorgi, VCJ De Boer, ... Cell 149 (1), 49-62, 2012 | 431 | 2012 |
| Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress–related genes A Carracedo, M Gironella, M Lorente, S Garcia, M Guzmán, G Velasco, ... Cancer research 66 (13), 6748-6755, 2006 | 423 | 2006 |
| A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis A Alimonti, C Nardella, Z Chen, JG Clohessy, A Carracedo, LC Trotman, ... The Journal of clinical investigation 120 (3), 681-693, 2010 | 414 | 2010 |
| The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells A Carracedo, M Lorente, A Egia, C Blázquez, S García, V Giroux, ... Cancer cell 9 (4), 301-312, 2006 | 411 | 2006 |
| Cannabinoid receptors as novel targets for the treatment of melanoma C Blázquez, A Carracedo, L Barrado, P José Real, ... The FASEB journal 20 (14), 2633-2635, 2006 | 327 | 2006 |
| PTEN level in tumor suppression: how much is too little? A Carracedo, A Alimonti, PP Pandolfi Cancer research 71 (3), 629-633, 2011 | 311 | 2011 |
| A metabolic prosurvival role for PML in breast cancer A Carracedo, D Weiss, AK Leliaert, M Bhasin, VCJ De Boer, G Laurent, ... The Journal of clinical investigation 122 (9), 3088-3100, 2012 | 280 | 2012 |
| Rewiring urea cycle metabolism in cancer to support anabolism R Keshet, P Szlosarek, A Carracedo, A Erez Nature Reviews Cancer 18 (10), 634-645, 2018 | 219 | 2018 |
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterVerified email at bidmc.harvard.edu
