| Durable antitumor responses to CD47 blockade require adaptive immune stimulation JT Sockolosky, M Dougan, JR Ingram, CCM Ho, MJ Kauke, SC Almo, ... Proceedings of the National Academy of Sciences 113 (19), E2646-E2654, 2016 | 332 | 2016 |
| Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes JT Sockolosky, E Trotta, G Parisi, L Picton, LL Su, AC Le, A Chhabra, ... Science 359 (6379), 1037-1042, 2018 | 291 | 2018 |
| The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy JT Sockolosky, FC Szoka Advanced drug delivery reviews 91, 109-124, 2015 | 223 | 2015 |
| Periplasmic production via the pET expression system of soluble, bioactive human growth hormone JT Sockolosky, FC Szoka Protein expression and purification 87 (2), 129-135, 2013 | 139 | 2013 |
| Localized CD47 blockade enhances immunotherapy for murine melanoma JR Ingram, OS Blomberg, JT Sockolosky, L Ali, FI Schmidt, N Pishesha, ... Proceedings of the National Academy of Sciences 114 (38), 10184-10189, 2017 | 118 | 2017 |
| Polymerase-guided base editing enables in vivo mutagenesis and rapid protein engineering A Cravens, OK Jamil, D Kong, JT Sockolosky, CD Smolke Nature Communications 12 (1), 1579, 2021 | 101 | 2021 |
| “Velcro” engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis CCM Ho, N Guo, JT Sockolosky, AM Ring, K Weiskopf, E Özkan, Y Mori, ... Journal of Biological Chemistry 290 (20), 12650-12663, 2015 | 93 | 2015 |
| Engineering neonatal Fc receptor-mediated recycling and transcytosis in recombinant proteins by short terminal peptide extensions JT Sockolosky, MR Tiffany, FC Szoka Proceedings of the National Academy of Sciences 109 (40), 16095-16100, 2012 | 75 | 2012 |
| A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia Q Zhang, ME Hresko, LK Picton, L Su, MJ Hollander, S Nunez-Cruz, ... Science translational medicine 13 (625), eabg6986, 2021 | 73 | 2021 |
| Engineering interferons and interleukins for cancer immunotherapy PG Holder, SA Lim, CS Huang, P Sharma, YS Dagdas, B Bulutoglu, ... Advanced drug delivery reviews 182, 114112, 2022 | 68 | 2022 |
| Decoupling the functional pleiotropy of stem cell factor by tuning c-Kit signaling CCM Ho, A Chhabra, P Starkl, PJ Schnorr, S Wilmes, I Moraga, HS Kwon, ... Cell 168 (6), 1041-1052. e18, 2017 | 68 | 2017 |
| Targeting the myeloid checkpoint receptor SIRPα potentiates innate and adaptive immune responses to promote anti-tumor activity TC Kuo, A Chen, O Harrabi, JT Sockolosky, A Zhang, E Sangalang, ... Journal of Hematology & Oncology 13, 1-19, 2020 | 55 | 2020 |
| Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice JT Sockolosky, S Kivimäe, FC Szoka PLoS One 9 (7), e102566, 2014 | 52 | 2014 |
| Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRPα J Sim, JT Sockolosky, E Sangalang, S Izquierdo, D Pedersen, ... MAbs 11 (6), 1036-1052, 2019 | 48 | 2019 |
| Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids HM Kieler-Ferguson, D Chan, J Sockolosky, L Finney, E Maxey, S Vogt, ... European Journal of Pharmaceutical Sciences 103, 85-93, 2017 | 40 | 2017 |
| Biologically relevant orthogonal cytokine/receptor pairs KC Garcia, J Sockolosky, L Picton US Patent 10,869,887, 2020 | 15 | 2020 |
| CD47 blockade enhances therapeutic activity of TCR mimic antibodies to ultra-low density cancer epitopes MD Mathias, JT Sockolosky, AY Chang, KS Tan, C Liu, KC Garcia, ... Leukemia 31 (10), 2254-2257, 2017 | 12 | 2017 |
| Biologically relevant orthogonal cytokine/receptor pairs KC Garcia, J Sockolosky, D Baker, C King US Patent 11,439,664, 2022 | 11 | 2022 |
| Velcro’engineering of high-affinity CD47 Ectodomain as SIRPalpha antagonists that enhance antibody-dependent cellular phagocytosis CC Ho, N Guo, JT Sockolosky, AM Ring, K Weiskopf, E Ozkan, Y Mori, ... J Biol Chem 290, 12650-63, 2015 | 3 | 2015 |
| Human orthogonal IL-2/IL-2Rβ as a tunable approach to enhance CD19-speific CAR-T cell antitumor activity Q Zhang, M Hresko, MJ Hollander, L Picton, L Su, S Nunez-Cruz, ... Blood 136, 48, 2020 | 2 | 2020 |
