Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide S Arenz, H Ramu, P Gupta, O Berninghausen, R Beckmann, ... Nature communications 5, 3501, 2014 | 153 | 2014 |
Regulation of gene expression by macrolide-induced ribosomal frameshifting P Gupta, K Kannan, AS Mankin, N Vázquez-Laslop Molecular cell 52 (5), 629-642, 2013 | 72 | 2013 |
Small molecule inhibitors of Clostridium difficile toxin B-induced cellular damage J Tam, GL Beilhartz, A Auger, P Gupta, AG Therien, RA Melnyk Chemistry & biology 22 (2), 175-185, 2015 | 70 | 2015 |
Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible P Gupta, S Sothiselvam, N Vázquez-Laslop, AS Mankin Nature communications 4, 1984, 2013 | 68 | 2013 |
Nascent peptide assists the ribosome in recognizing chemically distinct small molecules P Gupta, B Liu, D Klepacki, V Gupta, K Schulten, AS Mankin, ... Nature chemical biology 12 (3), 153, 2016 | 60 | 2016 |
Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor binding determinants P Gupta, Z Zhang, SN Sugiman-Marangos, J Tam, S Raman, JP Julien, ... Journal of Biological Chemistry, jbc. M117. 806687, 2017 | 58 | 2017 |
Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA YS Polikanov, T Szal, F Jiang, P Gupta, R Matsuda, M Shiozuka, TA Steitz, ... Molecular cell 56 (4), 541-550, 2014 | 55 | 2014 |
Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab LD Hernandez, HK Kroh, E Hsieh, X Yang, M Beaumont, PR Sheth, ... Journal of Molecular Biology 429 (7), 1030-1044, 2017 | 38 | 2017 |
Assays for Measuring C. difficile Toxin Activity and Inhibition in Mammalian Cells MA Cox, LD Hernandez, P Gupta, Z Zhang, F Racine, AG Therien Clostridium Difficile-A Comprehensive Overview, 2017 | 2 | 2017 |
Nascent Peptide and Small Molecule Mediated Translation Regulation P Gupta | | 2014 |