mike hann
mike hann
gsk.com üzerinde doğrulanmış e-posta adresine sahip
Alıntı yapanlar
Alıntı yapanlar
Molecular complexity and its impact on the probability of finding leads for drug discovery
MM Hann, AR Leach, G Harper
Journal of chemical information and computer sciences 41 (3), 856-864, 2001
Recap retrosynthetic combinatorial analysis procedure: a powerful new technique for identifying privileged molecular fragments with useful applications in combinatorial chemistry
XQ Lewell, DB Judd, SP Watson, MM Hann
Journal of chemical information and computer sciences 38 (3), 511-522, 1998
Type IIA topoisomerase inhibition by a new class of antibacterial agents
BD Bax, PF Chan, DS Eggleston, A Fosberry, DR Gentry, F Gorrec, ...
Nature 466 (7309), 935-940, 2010
Pursuing the leadlikeness concept in pharmaceutical research
MM Hann, TI Oprea
Current opinion in chemical biology 8 (3), 255-263, 2004
Finding the sweet spot: the role of nature and nurture in medicinal chemistry
MM Hann, GM Keserü
Nature reviews Drug discovery 11 (5), 355-365, 2012
Molecular obesity, potency and other addictions in drug discovery
MM Hann
MedChemComm 2 (5), 349-355, 2011
Strategic pooling of compounds for high-throughput screening
M Hann, B Hudson, X Lewell, R Lifely, L Miller, N Ramsden
Journal of chemical information and computer sciences 39 (5), 897-902, 1999
Fragment screening: an introduction
AR Leach, MM Hann, JN Burrows, EJ Griffen
Molecular BioSystems 2 (9), 429-446, 2006
Molecular complexity and fragment-based drug discovery: ten years on
AR Leach, MM Hann
Current opinion in chemical biology 15 (4), 489-496, 2011
The in silico world of virtual libraries
AR Leach, MM Hann
Drug discovery today 5 (8), 326-336, 2000
Design principles for fragment libraries: maximizing the value of learnings from pharma fragment-based drug discovery (FBDD) programs for use in academia
GM Keserű, DA Erlanson, GG Ferenczy, MM Hann, CW Murray, ...
Journal of medicinal chemistry 59 (18), 8189-8206, 2016
On the double bond isostere of the peptide bond: preparation of an enkephalin analogue
MM Hann, PG Sammes, PD Kennewell, JB Taylor
Journal of the Chemical Society, Perkin Transactions 1, 307-314, 1982
Behavior of cholesterol and its effect on head group and chain conformations in lipid bilayers: a molecular dynamics study
AJ Robinson, WG Richards, PJ Thomas, MM Hann
Biophysical journal 68 (1), 164-170, 1995
Chemoinformatics—a new name for an old problem?
M Hann, R Green
Current Opinion in Chemical Biology 3 (4), 379-383, 1999
Modulators of 14-3-3 protein–protein interactions
LM Stevers, E Sijbesma, M Botta, C MacKintosh, T Obsil, I Landrieu, ...
Journal of medicinal chemistry 61 (9), 3755-3778, 2017
Implementation of a system for reagent selection and library enumeration, profiling, and design
AR Leach, J Bradshaw, DVS Green, MM Hann, JJ Delany
Journal of chemical information and computer sciences 39 (6), 1161-1172, 1999
The synthesis and antiviral activity of 4-fluoro-1-β-D-ribofuranosyl-1H-pyrazole-3-carboxamide
R Storer, CJ Ashton, AD Baxter, MM Hann, CLP Marr, AM Mason, CL Mo, ...
Nucleosides, Nucleotides & Nucleic Acids 18 (2), 203-216, 1999
Stabilization of protein-protein interactions in drug discovery
SA Andrei, E Sijbesma, M Hann, J Davis, G O’Mahony, MWD Perry, ...
Expert Opinion on Drug Discovery 12 (9), 925-940, 2017
Head group and chain behavior in biological membranes: a molecular dynamics computer simulation
AJ Robinson, WG Richards, PJ Thomas, MM Hann
Biophysical journal 67 (6), 2345-2354, 1994
Molecular dynamics simulation of a hydrated phospholipid bilayer
JW Essex, MM Hann, WG Richards
Philosophical Transactions of the Royal Society of London. Series B …, 1994
Sistem, işlemi şu anda gerçekleştiremiyor. Daha sonra yeniden deneyin.
Makaleler 1–20