Ajit Jadhav
Ajit Jadhav
mail.nih.gov üzerinde doğrulanmış e-posta adresine sahip
Alıntı yapanlar
Alıntı yapanlar
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ...
Nature biotechnology 34 (8), 828-837, 2016
Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries
J Inglese, DS Auld, A Jadhav, RL Johnson, A Simeonov, A Yasgar, ...
Proceedings of the National Academy of Sciences 103 (31), 11473-11478, 2006
The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
R Huang, N Southall, Y Wang, A Yasgar, P Shinn, A Jadhav, DT Nguyen, ...
Science translational medicine 3 (80), 80ps16-80ps16, 2011
A high-throughput screen for aggregation-based inhibition in a large compound library
BY Feng, A Simeonov, A Jadhav, K Babaoglu, J Inglese, BK Shoichet, ...
Journal of medicinal chemistry 50 (10), 2385-2390, 2007
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
LAM Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, IS Goldlust, ...
Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
FJ Najm, M Madhavan, A Zaremba, E Shick, RT Karl, DC Factor, TE Miller, ...
Nature 522 (7555), 216-220, 2015
Compound cytotoxicity profiling using quantitative high-throughput screening
M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ...
Environmental health perspectives 116 (3), 284-291, 2008
Fluorescence spectroscopic profiling of compound libraries
A Simeonov, A Jadhav, CJ Thomas, Y Wang, R Huang, NT Southall, ...
Journal of medicinal chemistry 51 (8), 2363-2371, 2008
Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors
RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ...
Journal of medicinal chemistry 53 (13), 4891-4905, 2010
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease
A Jadhav, RS Ferreira, C Klumpp, BT Mott, CP Austin, J Inglese, ...
Journal of medicinal chemistry 53 (1), 37-51, 2010
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a
F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ...
Journal of medicinal chemistry 52 (24), 7950-7953, 2009
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors
ONF King, XS Li, M Sakurai, A Kawamura, NR Rose, SS Ng, AM Quinn, ...
PloS one 5 (11), e15535, 2010
Characterization of chemical libraries for luciferase inhibitory activity
DS Auld, NT Southall, A Jadhav, RL Johnson, DJ Diller, A Simeonov, ...
Journal of medicinal chemistry 51 (8), 2372-2386, 2008
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2, 4-diamino-7-aminoalkoxy-quinazolines.
F Liu, X Chen, A Allali-Hassani, AM Quinn, TJ Wigle, GA Wasney, A Dong, ...
Journal of medicinal chemistry 53 (15), 5844-5857, 2010
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
Selective and cell-active inhibitors of the USP1/UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells
J Chen, TS Dexheimer, Y Ai, Q Liang, MA Villamil, J Inglese, DJ Maloney, ...
Chemistry & biology 18 (11), 1390-1400, 2011
Comprehensive mechanistic analysis of hits from high-throughput and docking screens against β-lactamase
K Babaoglu, A Simeonov, JJ Irwin, ME Nelson, B Feng, CJ Thomas, ...
Journal of medicinal chemistry 51 (8), 2502-2511, 2008
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317, 2018
Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease
W Zheng, J Padia, DJ Urban, A Jadhav, O Goker-Alpan, A Simeonov, ...
Proceedings of the National Academy of Sciences 104 (32), 13192-13197, 2007
A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses
Q Liang, TS Dexheimer, P Zhang, AS Rosenthal, MA Villamil, C You, ...
Nature chemical biology 10 (4), 298, 2014
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Makaleler 1–20